Chronic Limb Ischemia
Conditions
Brief summary
The femoro-popliteal arterial segment is one of the most frequent locations for atherosclerosis. Its management is mainly endovascular (standard and coated-balloon angioplasty, stenting). However, the structural features of the atherosclerotic disease in regards to patient's risk factors and past medical and surgical histories are not well studied. Furthermore, the histological analysis of the femoro-popliteal arterial segment is rare in the literature, and made difficult mostly because of the length of this segment. There is a clinical need for better understanding of atherosclerotic lesions in this location, with as further goal, a better management of this disease.
Interventions
PROCEDUREExplantation of the femoro-popliteal arterial segment from the amputed limb
Explantation of the femoro-popliteal arterial segment from the amputed limb
Sponsors
University Hospital, Strasbourg, France
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Age \> 18 years old * Men and women * Patient with chronic limb ischemia that is scheduled for transfemoral amputation in the University Hospital of Strasbourg * Patient giving his -non-opposition to the explantation and use of the femoro-popliteal arterial segment
Exclusion criteria
* Refusal to give his consent * Impossibility to give clear information to the patient * Pregnant and breastfeeding women * Patient under administrative protection
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Descriptive analysis of the arterial structure in micro-CT. | 3 years | study precisely the pathological structure of the femoro-popliteal arterial segment in AOMI, both in imaging and histologically. |
Countries
France
Contacts
Primary ContactNabil CHAKFE
Outcome results
None listed