Topical Calcipotriol Versus Narrowband Ultraviolet B in Treatment of Alopecia Areata

Topical Calcipotriol Versus Narrowband Ultraviolet B in Treatment of Alopecia Areata: A Randomized Controlled Trial

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT03847441

Enrollment

Registered

2019-02-20

Start date

2017-10-01

Completion date

2018-12-31

Last updated

2019-04-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Alopecia Areata

Keywords

Alopecia Areata, Calcipotriol, Narrow Band-UVB, Vitamin D3

Brief summary

Alopecia Areata is a common condition. This study investigated the efficacy of calcipotriol versus Narrow Band Ultraviolet B in treatment of Alopecia areata and their effects on serum vitamin D3 levels.

Interventions

DRUGCalcipotriol

Calcipotriol ointment (0.005%)

DEVICENarrow Band UVB

NB-UVB (311nm) phototherapy

DIAGNOSTIC_TESTvitamin D3 level

vitamin D3 (ng/ml)

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

14 Years to 40 Years

Healthy volunteers

Inclusion criteria

* Alopecia Areata of scalp

Exclusion criteria

Other causes of alopecias including scarring alopecia, androgenic alopecia, telogen effluvium autoimmune diseases, pregnant and lactating females

Design outcomes

Primary

Measure	Time frame	Description
Clinical improvement of Alopecia Areata After treatment As assessed by Severity of Alopecia tool (SALT) score	3 months	calculation of SALT score before and after treatment
Improvement of serum Vitamin D levels in (ng/ml) after treatment	3 months	measurement of serum vitamin D before and after treatment

Countries

Egypt

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026