Exercise Performance
Conditions
Brief summary
In this randomized double-blind, placebo-controlled, crossover pilot trial, we evaluated the effects of 7-day H2 inhalation on exercise performance outcomes and serum hormonal and inflammation profiles in a cohort of young men and women.
Detailed description
All participants were allocated to receive either gaseous hydrogen (4%) or placebo (room air) by 20-min once-per-day inhalation for 7 days, with wash-out period of 7 days to prevent the residual effects of interventions across study periods. The primary treatment outcome was the change in running time-to-exhaustion from baseline to day 7. Additionally, assessment of other exercise performance endpoints and clinical chemistry biomarkers were performed at baseline and after 7 days after each intervention.
Interventions
OTHERPlacebo
Inhalation of room air for 20 min per day during 7 days
OTHERHydrogen
Inhalation of 4% hydrogen for 20 min per day during 7 days
Sponsors
University of Novi Sad, Faculty of Sport and Physical Education
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
BASIC_SCIENCE
Masking
DOUBLE (Subject, Investigator)
Eligibility
Sex/Gender
ALL
Age
18 Years to 35 Years
Healthy volunteers
Yes
Inclusion criteria
Age ≥ 18 -35 years Body mass index 20 - 25 kg/m2 Free of major diseases Physically active Must be able to give written informed consent
Exclusion criteria
Use of any dietary supplements within 4 weeks before study commences Abnormal values for lab clinical chemistry (\> 2 SD)
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change in exercise performance | Change from baseline running time-to-exhaustion at 7 days | Running time-to-exhaustion |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Change in exercise performance | Change from baseline maximal voluntary isometric strength at 7 days | Maximal voluntary isometric strength |
| Change in clinical chemistry biomarker | Change from baseline serum insulin at 7 days | Insulin |
Countries
Serbia
Outcome results
None listed