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Clinical Study of Titrating PEEP of Different Methods on Right Heart Function

Clinical Study of Titrating PEEP of Different Methods on Right Heart Function and Pulmonary Artery Pressure in ARDS Patients

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT03845556
Enrollment
30
Registered
2019-02-19
Start date
2018-08-04
Completion date
2019-03-30
Last updated
2019-02-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

ARDS, Human

Brief summary

To observe the influence of different methods titrating PEEP on right heart function and pulmonary artery pressure in ARDS patients .

Detailed description

30 patients who diagnosed as ARDS were included in this study.Then set PEEP with respectively ARDS net 、EIT and Esophageal Pressure in Breathing Machine . Recorded diameter of right and left ventricular TAM TAPSE pulmonary artery pressure.Objective to evaluate the correlation between the level of PEEP in three methods and the right heart function and pulmonary artery pressure in ARDS patients .

Interventions

None listed

Sponsors

Zhongda Hospital
CollaboratorOTHER
Southeast University, China
Lead SponsorOTHER

Study design

Observational model
CASE_ONLY
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to 80 Years
Healthy volunteers
No

Inclusion criteria

* Patients admitted to ICU diagnosed of modecate to severe ARDS (Berlin criteria) * Patients age between 18 years old and 80 years

Exclusion criteria

* Patients with chronic respiratory diseases such as COPD. * Ventilated because of oesophageal surgery in the previous 12months. * Patients who cannot obtain clear ultrasound images due to thoracic surgery ,massive pleural effusion. * Oesophageal bleeding in previous 30 days history of oesophageal varices. * Facial trauma and surgery.

Design outcomes

Primary

MeasureTime frameDescription
the function of right heart and pulmonary artery pressure2018.4-2019.3Systolic Pulmonary Artery Pressure TAPSE or Tricuspid Annular Motion orTricuspid annular plane systolic excursion or right ventricular diameter or right left ventricular diameter ratio in diffrient PEEP

Countries

China

Contacts

Primary ContactDutong Yue, Dr
1475008526@qq.com15051887681
Backup ContactGuoFeng Mei, Dr
13813841261@139.com13813841261

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026