Transnasal Humidified Rapid-Insufflation Ventilatory Exchange (THRIVE) Could Decrease the Incidence of Oxygen Desaturation During Suspension Laryngoscopy: a Randomized Controlled Trial (Optilaryngo)

Transnasal Humidified Rapid-Insufflation Ventilatory Exchange (THRIVE) Could Decrease the Incidence of Oxygen Desaturation During Suspension Laryngoscopy: a Randomized Controlled Trial

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT03843580

Acronym

optilaryngo

Enrollment

Registered

2019-02-18

Start date

2019-04-23

Completion date

2022-02-10

Last updated

2022-02-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Apnea, Postanesthetic, Desaturation of Blood, Apnea, Anesthesia, Larynx Disease, Pharynx; Anomaly

Keywords

Time of apnea, Optiflow, Thrive, Apnea oxygenation, Suspension laryngoscopy, General Anesthesia, Oxygenation apnea

Brief summary

Suspension laryngoscopy is realised during apnea. In effect, surgeons are in the mouth of the patient and we can't have access at the aiways. So investigators like to use a Transnasal Humidified Rapid-Insufflation Ventilatory Exchange (THRIVE) to increase time of apnea and decrease the impact of oxygen desaturation.

Interventions

DEVICEoptiflow

we use Transnasal Humidified Rapid-Insufflation Ventilatory Exchange (thrive-optiflow) during general anesthesia for suspension laryngoscopy

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* suspension laryngoscopy

Exclusion criteria

* THRIVE contraindication: * epistaxis * undrained pneumothorax * Recent gastroesophageal surgery (1months) * Skull Fractures

Design outcomes

Primary

Measure	Time frame	Description
desaturation defined as the number of patient who presented at least one desaturation during suspension laryngoscopy	Two hours	the number of patient who presented at least one desaturation during suspension laryngoscopy. An oxygen desaturation define like SpO2\<96%

Secondary

Measure	Time frame	Description
hypoxemia (decrease the number of Hypoxemia event define like SpO2<90%)	2 hours	Decrease the number of Hypoxemia event define like SpO2\<90%
side effect	2 hours	decrease the number of side effects

Other

Measure	Time frame	Description
time of apnea	2 hours	increase time of apnea with THRIVE

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026