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Mini-fluid Challenge as a Predictor of Fluid Response for Pneumoperitoneum Patient

Mini-fluid Challenge as a Predictor of Fluid Response for Pneumoperitoneum Patient

Status
Withdrawn
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT03843411
Enrollment
0
Registered
2019-02-18
Start date
2019-10-31
Completion date
2020-10-31
Last updated
2020-01-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anesthesia

Keywords

mini-fluid challenge

Brief summary

The purpose of this study is to evaluate whether the change of stroke volume index(△SVI) induced by the rapid mini-fluid administration can predict fluid responsiveness in patients with pneumoperitoneum

Detailed description

Perioperative fluid management is significant important during surgery. The current trend tends to use goal-directed fluid therapy in surgery. Goal-directed fluid therapy refers to continuous monitoring of hemodynamic parameters during surgery and managing more accurate fluid administration based on the data obtained while promoting optimal tissue perfusion. Define fluid responsiveness with the hemodynamic parameters as to whether the cardiac output can be significantly increased after administration of fluid. Therefore, the advantage of predicting fluid responsiveness is that it can optimize the cardiac output and tissue perfusion while avoiding administering unnecessary fluid to patients. The purpose of this study is to evaluate whether the change of stroke volume index(△SVI) induced by the rapid mini-fluid administration can predict fluid responsiveness in patients with pneumoperitoneum.

Interventions

None listed

Sponsors

Changhua Christian Hospital
Lead SponsorOTHER

Study design

Observational model
CASE_CROSSOVER
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
20 Years to 70 Years
Healthy volunteers
No

Inclusion criteria

* receive operation that required pneumoperitoneum and FloTrac monitoring * ASA 1\ 3 * age between 20 to 70 year old

Exclusion criteria

* patient who cannot understand the process and aim of the study * patient with arrhythmia * poor heart function(LVEF\<50%, severe valvular disease, CAD) * CKD * pregnant patient * patients allergic to voluven

Design outcomes

Primary

MeasureTime frameDescription
change of stroke volume index1 hoursrecord stroke volume index before and after mini-fluid challenge

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026