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Mindfulness-Based Health Promotion Program for Educators (MBHP - Educa).

Development and Implementation of Mindfulness-Based Health Promotion Program for Educators (MBHP - Educa): Evaluation of Cognitive Functions and Epigenetic Modifications.

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT03839030
Acronym
Mindfulness
Enrollment
146
Registered
2019-02-12
Start date
2018-03-05
Completion date
2020-07-05
Last updated
2021-03-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Burnout Syndrome, Cognitive Impairment, Stress

Brief summary

In the last few decades, the world has seen a significant increase in the occurrence of occupational diseases related to Burnout Syndrome (professional exhaustion) and stress in educators. These disorders affect mental health and teaching activity. In this way, they need to develop socio-emotional skills to cope with the psychosocial stressors related to the school environment. Currently, mindfulness-based therapies have been recommended to help educators acquire emotional self-control, and to improve self-esteem, metacognition, attention, resilience and affectivity, in addition to better the social skills needed in the school milieu. The main objective of the proposed research project is to elaborate a program of Mindfulness-Based Health Promotion - educators (MBHP - educa) to be applied to a population of Brazilian public school educators. The efficacy of the program will be evaluated by cognitive testing. Blood tests for the above-mentioned stress-related molecules will be performed. The goal of developing the MBHP - educa Program is to promote and ameliorate the health care of public school teachers. Developing such a research proposal will contribute to debate and implement public health policies focussed on promoting the health of public school teachers in Brazil.

Detailed description

In the last few decades, the world has seen a significant increase in the occurrence of occupational diseases related to Burnout Syndrome (professional exhaustion) and stress in educators. These disorders affect mental health and teaching activity. In this way, they need to develop socio-emotional skills to cope with the psychosocial stressors related to the school environment. Currently, mindfulness-based therapies have been recommended to help educators acquire emotional self-control, and to improve self-esteem, metacognition, attention, resilience and affectivity, in addition to better the social skills needed in the school milieu. A few published studies indicate that mindfulness practices also reduce some inflammation- and stress- related molecules such as cortisol, receptor-interacting serine/threonine kinase 2 (RIPK2), cyclooxygenase 2 (COX2), interleukin 6 (IL-6), tumor necrosis factor-α (TNF-α) and epigenetic-regulation related histone deacetilases (HDAC). These indicator molecules can be measured in blood. The World Health Organisation (WHO-2013) recommends the worldwide implementation of strategies for the promotion of mental health, which are particularly aimed at preventing occupational diseases. The main objective of the proposed research project is to elaborate a program of Mindfulness-Based Health Promotion - educators (MBHP - educa) to be applied to a population of Brazilian public school educators. The efficacy of the program will be evaluated by cognitive testing. Blood tests for the above-mentioned stress-related molecules will be performed. The goal of developing the MBHP - educa Program is to promote and ameliorate the health care of public school teachers. Developing such a research proposal will contribute to debate and implement public health policies focussed on promoting the health of public school teachers in Brazil.

Interventions

OTHERMBHP-Educa

This intervention is a meditative practice which the individuals will practice in their daily life following the MBHP-educa protocol

Sponsors

Marcelo Demarzo, MD, PhD
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
SINGLE (Subject)

Eligibility

Sex/Gender
FEMALE
Age
23 Years to 65 Years
Healthy volunteers
Yes

Inclusion criteria

1)Brazilian male or female aged between 23 and 65 years and (2) currently working in the classroom

Exclusion criteria

(1) the presence of medical conditions or medications use that might affect inflammatory pathways; (2) report of an infectious condition in the last 15 days before collecting a blood sample; (3) active psychiatric and/or clinical comorbidities potentially life-threatening such as psychosis or suicidal ideation; and (4) had previously practiced or currently practicing meditation, yoga or Tai-Chi

Design outcomes

Primary

MeasureTime frameDescription
World Health Organization Quality of Life-BREF (WHOQOL-BREF)Pre-test, Post-test and follow-up (12 months)To evaluate quality of life through five subscales: physical domain - mean of responses psychological domain - mean of responses relationships domain - mean of responses environment domain - mean of responses quality of life and perception of life - mean of responses \*each question response range one to five points Higher scores - Better Quality of Life
Morningness-eveningness questionnaire - sum *Range 16 to 86 *higher scorer - more morningness typePre-test, Post-test and follow-up (12 months)To evaluate person's circadian rhythm (biological clock) (sum of all responses)
Pittsburgh Sleep Quality IndexPre-test, Post-test and follow-up (12 months)To evaluate the Sleep Quality - sum of responses score \*each questions have a specific conversion to range zero to six Higher scores - better sleep quality

Secondary

MeasureTime frameDescription
Glutathione metabolism from blood samplesPre-test, Post-test and follow-up (12 months)GSH plasma levels, Cysteine and homocisteine serum levels
Perceived Stress Scale (PSS-10)Pre-test, Post-test and follow-up (12 months)to evaluate the level of subjectively noticed stress, composed of 10 items
Determination of cytokine levels in serum samples.Pre-test, Post-test and follow-up (12 months)To evaluate the interleukin-8 (IL-8), interleukin-1β (IL-1β), interleukin-6 (IL-6), interleukin-10 (IL-10), tumor necrosis factor (TNF) e interleukin-12p70 (IL-12p70) \*Concentration in micromol per liter. (mean and standard deviation, median and quartile per groups)
Connor-Davidson Resilience Rating ScalePre-test, Post-test and follow-up (12 months)The CD-RISC is a 25-item measure of resilience.
Positive and Negative Affect Schedule (PANAS)Pre-test, Post-test and follow-up (12 months)To evaluate positive and negative Affect through two subscales: positive affect - sum negative affect - sum * each question range one to five * higher score - more frequent

Other

MeasureTime frameDescription
Rey Auditory-Verbal Learning Test - RAVLTPre-test, Post-test and follow-up (12 months)To evaluate memory (number of word remember)
Digit span testPre-test, Post-test and follow-up (12 months)To evaluate work memory (maximum lenght)
Stroop testPre-test, Post-test and follow-up (12 months)To evaluate attention and inhibitory behavior (number of errors and time)
Trail Making Test - TMTPre-test, Post-test and follow-up (12 months)To evaluate attention (time to trail every letter or/and number)
Hospital Anxiety and Depression Scale (HAADS)Pre-test, Post-test and follow-up (12 months)To evaluate anxiety and depression symptoms through two subscales: anxiety - sum depression - sum * each question range zero to four * higher score - more symptons
Burnout Clinical Subtypes Questionnaire - BCSQ-12Pre-test, Post-test and follow-up (12 months)To evaluate the burnout clinical subtypes through three subscales: Overload - mean, standard deviation and median Lack of development - mean, standard deviation and median Neglect - mean, standard deviation and median \*each question response range one to seven points Higher scores - More Symptons of Burnout
Five Facet Mindfulness Questionnaire (FFMQ)Pre-test, Post-test and follow-up (12 months)To evaluate the mindfulness trace through five subscales: OBSERVING - mean DESCRIBING - mean NONJUDGE - mean NONREACT - mean ATC WITH AWARENESS - mean * each question range one to five * higher score - more mindful

Countries

Brazil

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026