Comparison Between Uterine Artery Doppler and Placental Vascular Indices in Prediction of Preeclampsia

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT03838887

Enrollment

100

Registered

2019-02-12

Start date

2021-06-01

Completion date

2022-01-01

Last updated

2021-08-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pre-Eclampsia

Brief summary

• Preeclampsia is a multisystem disorder that can cause considerable maternal and fetal morbidity and mortality. Late preeclampsia (with delivery \>34 weeks) is more frequent and less serious than early preeclampsia (with delivery \<34 weeks). Poor early placentation has been especially associated with early disease. Early identification of women at risk of preeclampsia is currently a crucial aim of antenatal care since they may benefit from prophylactic treatment and increased surveillance.

Detailed description

* The introduction of three-dimensional (3D) ultrasound techniques, with the option of calculating placental volume and measuring vascular indices, has created an excellent opportunity to study early changes in the uteroplacental circulation space, which includes the maternal spiral arteries and the intervillous space. This technology may allow a more direct evaluation of the abnormal placentation process thought to herald the development of preeclampsia. * The aim of this study was to assess the usefulness of placental volume and 3D vascular indices as reliable predictors of early preeclampsia in comparison to uterine artery Doppler

Interventions

DEVICEultrasound machine

Ultrasound machine with a vocal software

Study design

Observational model

CASE_CONTROL

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

FEMALE

Age

18 Years to 35 Years

Healthy volunteers

Yes

Inclusion criteria

* A. Control group: Pregnant women: 1. Age between 18-35 years 2. Parity: primigravidas and multiparas. 3. Have no history of preeclampsia or eclampsia. 4. Have no history of chronic hypertension. 5. Not diabetic. 6. Not have antiphospholipid syndrome. 7. Not have autoimmune disease such as SLE. B. High risk group: Pregnant women with: 1. History of preeclampsia -Eclapmsia 2. Chronic hypertension 3. Diabetic 4. Antiphospholipid syndrome. 5. Autoimmune syndrome such as SLE.

Exclusion criteria

* • Smoking * Dichorionic placentae * Fetal anomaly * Uterine fibroid at the site of placental implantation * Subchorionic hematoma

Design outcomes

Primary

Measure	Time frame	Description
placental vascular indices in prediction of preeclampsia	one year	placental vascular indices in prediction of preeclampsia compared to uterine artery doppler in prediction of preeclampsia

Countries

Egypt

Contacts

Primary ContactSHERIF MOHAMMED ELSIRGANY, DOCTOR

SHERIFELSIRGANY@YAHOO.COM+201223607191

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026