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Effects of 6 Weeks High-intensity Interval Training Among Spinal Cord Injury

Effects of 6 Weeks High-intensity Interval Training on Muscle Strength and Cardiorespiratory Response Among Spinal Cord Injury

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT03837834
Enrollment
8
Registered
2019-02-12
Start date
2019-02-15
Completion date
2019-09-05
Last updated
2019-09-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

INCOMPLETE SPINAL CORD INJURY (ASIA D)

Keywords

HIGH INTENSITY INTERVAL TRAINING, INCOMPLETE SPINAL CORD INJURY, MUSCLE STRENGTH, CARDIO-RESPIRATORY FITNESS

Brief summary

The training consists of 6 weeks of functional electrical stimulation leg cycling exercise (FES-LCE) program. The training program comprises of 2 visits per week. Each visit consists of FES-LCE for 45 minutes. Throughout the 6 weeks program, there will be testing/assessment sessions on week 1, week 3 and week 6. The FES will be applied via surface electrodes and the stimulation intensity based on the participant's tolerance level.

Interventions

OTHERFunctional Electrical Stimulation Leg Cycling Exercise

FES- leg cycling for 45 minutes (3 min warm up + 40 min HIIT + 2 min cooldown). The FES will be applied via surface electrodes and the stimulation intensity based on your tolerance level.

Sponsors

University of Malaya
CollaboratorOTHER
Universiti Teknologi Mara
Lead SponsorOTHER

Study design

Allocation
NON_RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
TREATMENT
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
No

Inclusion criteria

* Participants were diagnosed with incomplete spinal cord injury (SCI) at least one year prior to participation. * Age between 18-75 years old. * Both male and female. * Have at least 90º bilateral knee flexion. * Moderate neurological induce weakness in quadriceps muscle of 1 leg that is responsive to electrical stimulation (moderate weakness was defined as 3/5 or 4/5 on manual muscle testing). * Able to perform cycling activity. * Normal upper limb function. * Able to follow command.

Exclusion criteria

* Had a recent history of trauma to the lower limb. * Severely infected skin pressure sore on weight-bearing skin areas. * Illness caused by acute urinary tract infection. * Uncontrolled spasticity or pain. * History of cardiovascular/cardiorespiratory problem. * Orthostatic hypotension. * Unhealed decubiti at electrode placement area. * Recurrent autonomic dysreflexia. * Active heterotopic ossification. * Other peripheral or central neurologic injury.

Design outcomes

Primary

MeasureTime frameDescription
Changes of peak torque of Quadriceps and HamstringChanges of peak torque at 6 weekIsometric peak torque for quadriceps and hamstring will be measured using Biodex isokinetic machine.

Secondary

MeasureTime frameDescription
Changes of peak VO2Changes of peak VO2 at 6 weekPeak VO2 will be measured using Cosmed Quark CPET system apparatus

Countries

Malaysia

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026