Sensory Modulation Disorder, Sensory Over-Responsivity
Conditions
Keywords
Neurofeedback, Sensory Modulation Disorder, Sensory Over-Responsivity
Brief summary
Sensory Over-Responsivity (SOR) is characterized by a disruption in regulating sensory stimuli and can significantly impact pain perception and restrict daily participation and quality of life. Altered neurophysiological processes in SOR are documented, revealing reduced electroencephalogram at rest and P300 amplitudes, the latter tested through event-related potentials (ERP). Both may explain the failure to regulate incoming sensory stimuli. Neurofeedback (NF) therapy, a remedial treatment approach, aims at self-regulating the brain's neural activity and has proven its efficiency in treating comorbid SMD syndromes. Our study aims to investigate NF therapy efficiency in decreasing pain sensitivity, enhancing auditory ERP components of P300, increasing the power of the alpha band, life-satisfaction and Goal Attainment Scaling (GAS) scores in adults with SOR.
Detailed description
In this serial experimental research design, 10 individuals with SOR aged 21-45 years will participate. A medical and demographic questionnaire and the Sensory Responsiveness Questionnaire-Intensity Scale (SRQ-IS) will be applied to screen for participation eligibility. Outcome measures will be conducted at 4-time points (1. baseline- 3 weeks pre-treatment; 2. before the first treatment session; 3. after the last treatment session; and 4. a month post-treatment) applying: The Goal Attainment Scaling (GAS), the P300 component using a neurophysiological assessment of the 'Oddball paradigm', the alpha power using electroencephalogram resting state, and electronic versions of the Satisfaction with Life Scale, the World Health Organization Disability Assessment Schedule, and the Pain Sensitivity Questionnaire. Sixteen individually therapy sessions of 45 minutes each, twice a week, will be held at the same time of day. Repeated measures ANOVA or a non-parametric equivalent will be used to analyze the dependent variables measures change over time.
Interventions
DEVICENeurofeedback treatment
A treatment that developed to train adults with sensory modulation disorder by applying EEG (Curry 7 EEG system, Neuroscan-Compumedics). This treatment will aim to normalize the Alpha power (amplitude).
Sponsors
Tel Aviv University
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE
Masking description
The researcher that will perform the measurement assessments will differ from the one that will provide the therapy sessions.
Intervention model description
it is a serial experimental research design, which includes 10 individuals with sensory over responsivity aged 21-45 years will participate
Eligibility
Sex/Gender
ALL
Age
21 Years to 45 Years
Healthy volunteers
Yes
Inclusion criteria
1. Having SOR indicated by a score higher than 2.39 on the Sensory Responsiveness Questionnaire-Aversive scale. 2. free of analgesic medicines for no less than 24 hours before the sessions. 3. independent functioning in the community. 4. fluency in understanding and reading Hebrew
Exclusion criteria
1. metabolic, psychiatric, neurological, or neuro-developmental, but ADHD diagnosis 2. acute or chronic pain. 3. regular intake of neurological, psychiatric and analgesic medicines. 4. participating in other therapies (i.e., cognitive therapies) at present. 5. substance abuse. 6. pregnancy.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| The Satisfaction with Life Scale (SWLS) | assesses the change between the baseline (3 weeks pre-treatment), and after 28 days from the last treatment session | assesses global life satisfaction |
| Goal Attainment Scaling (GAS) | assesses the change between the baseline (3 weeks pre-treatment), and after 28 days from the last treatment session | a standardized therapeutic method used to evaluate the participants' progress toward their functional goals |
| The World Health Organization Disability Assessment Schedule (WHODAS-2.0) | assesses the change between the baseline (3 weeks pre-treatment), and after 28 days from the last treatment session | To evaluate participants' participation level in the last month |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Pain Sensitivity Questionnaire (PSQ) | 3 weeks pre-treatment, 2 days before first treatment session, two days after the last treatment session and after month of the treatment | a standardized self-report questionnaire assessing daily pain sensitivity |
| Electroencephalogram (EEG) Resting State | 3 weeks pre-treatment, 2 days before first treatment session, two days after the last treatment session and after month of the treatment | To measure alpha band (8-12Hz) power |
Other
| Measure | Time frame | Description |
|---|---|---|
| Auditory Evoked Related Potentials (AERP) | 3 weeks pre-treatment, 2 days before first treatment session, two days after the last treatment session and after month of the treatment | Change from Baseline to 28 days after the last treatment session: An EEG method will be used to evaluate the brain responses to auditory stimulus. |
Countries
Israel
Outcome results
None listed