The Ability of NIRS to Predict Brain Injury in Hypoxic Ischemic Encephalopathy

The Ability of Near Infrared Spectroscopy Monitoring During Hypothermia Treatment to Predict Brain Injury in Infants With Hypoxic Ischemic Encephalopathy

Status

Terminated

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT03835039

Enrollment

101

Registered

2019-02-08

Start date

2019-01-03

Completion date

2022-01-01

Last updated

2022-03-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

HIE - Perinatal Hypoxic - Ischemic Encephalopathy

Brief summary

A longitudinal study evaluating the predictive ability of near infrared spectroscopy to predict brain injury in infants with hypoxic ischemic encephalopathy. Data will be analyzed at two different time periods, at discharge and again at 2 years of age.

Interventions

DEVICENIRS

Monitoring cerebral and perirenal perfusion using NIRS

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

1 Minutes to 2 Years

Healthy volunteers

Inclusion criteria

* Infants with diagnosis at birth of HIE

Exclusion criteria

* none

Design outcomes

Primary

Measure	Time frame	Description
MRI findings of encephalopathy	6 days	MRI studies will be reviewed and assessed for markers of HIE including damage to deep grey matter structures.
Neurodevelopment at 2 years of age	2 years	Bayleys developmental test will be used to categorize the infants' neurodevelopment at 2 years of age.

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026