Colonic Polyps
Conditions
Brief summary
This clinical trial is being conducted to compare the efficacy and safety of two standard methods of polypectomy，Conventional Endoscopic Mucosal Resection（EMR）and Underwater Endoscopic Mucosal Resection（UEMR），for small colorectal polyps.
Interventions
BEHAVIORALUnderwater EMR
Polypectomy is performed under full water emersion without the use of submucosal injection.
Sponsors
Ningbo No. 1 Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 75 Years
Healthy volunteers
No
Inclusion criteria
Patients age between 18-75 years old with non-pedunculated colonic polyps (measuring between 4 and 9mm), who willing to participate in this study.
Exclusion criteria
1. pregnancy, 2. inflammatory bowel disease, 3. familial polyposis 4. the use of anticoagulant therapy or antiplatelet therapy 5. the absence of informed patient consent. 6. Polyps showing signs of deep submucosal invasion
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| complete resection rate | 7 days | complete resection rate is defined as a complete en bloc resection of a lesion with tumor-free lateral and vertical margins. |
| En bloc resection rate | immediately | En bloc resection rate was defined as the entire lesion could be removed in 1 piece instead of piecemeal resection. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Adverse event rate | 14 days | Including bleeding and perforation , etc. |
| Procedure time | 24 hours | Time to execute the program |
Countries
China
Outcome results
None listed