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Constitution of ex Vivo Ovarian Tumor Models for the Validation of the Interest of Innovative Therapies and the Search for Tumor or Circulating Biomarkers Predictive of Treatment Response

Constitution of ex Vivo Ovarian Tumor Models for the Validation of the Interest of Innovative Therapies and the Search for Tumor or Circulating Biomarkers Predictive of Treatment Response

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT03831230
Acronym
OVAREX
Enrollment
250
Registered
2019-02-05
Start date
2019-03-07
Completion date
2025-02-27
Last updated
2025-08-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ovarian Cancer

Keywords

ex vivo, predictive tests, tumor models

Brief summary

Development of ex vivo models of ovarian cancer, fallopian tubes or peritoneum.

Interventions

GENETICcollection of blood, urine, tumor and ascite samples

collection of blood, urine, tumor and ascite samples during ovarian surgery

Sponsors

Centre Francois Baclesse
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
FEMALE
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Patient over 18 years old. * Patient with ovarian cancer, carcinoma of the fallopian tubes, or histologically proven peritoneum. All FIGO stages are accepted for the study. * Patient to be managed by surgery (laparoscopy and / or laparotomy).

Exclusion criteria

* Pregnant woman * Persons deprived of liberty or guardianship (including curatorship) * History of any other clinically active malignancy in the last 5 years prior to inclusion

Design outcomes

Primary

MeasureTime frameDescription
Rates of exploitable ex vivo tumor, blood and urine samples for performing predictive testsCollection of blood, urine, tumor and ascite samples at the time of ovarian surgeryNumber and quality of tumor, blood and urine samples that can be used to perform predictive tests of the response to treatment

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 7, 2026