Usefulness of Capillary Refill Time and Skin Mottling Score to Predict Intensive Care Unit Admission

Contribution of Capillary Refilling Time and Skin Mottling Score to Predict Intensive Care Unit Admission of Patients With Septic or Haemorrhagic Shock Admitted to the Emergency Department

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT03831022

Acronym

TRCMARBSAU

Enrollment

1500

Registered

2019-02-05

Start date

2018-12-17

Completion date

2020-12-17

Last updated

2019-02-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Shock, Hemorrhagic, Shock, Septic

Keywords

shock, sepsis, haemoragy, intensive care unit, prediction

Brief summary

In the emergency department (ED), the severity assessment of shock is a fundamental step prior to the admission in intensive care unit (ICU). As biomarkers are time consuming to evaluate severity of the micro and macro-circulation alteration, capillary refill time and skin mottling score are 2 simples, available clinical criteria validated to predict mortality in the ICU. The aim of this study is to provide clinical evidence that capillary refill time and skin mottling score assessed in the ED also predict ICU admission of patients with septic or haemorrhagic shock.

Detailed description

This trial is an observational, non-randomized controlled study. A total of 1500 patients admitted to the ED for a septic or hemorrhagic shock will be followed. The primary outcome is the admission to the ICU. The study will not impact the treatments provided to each patient. Capillary refill time and skin mottling score will not be taken into account to decide patient's treatments and/or ICU admission. Patients will be followed during their hospital stay in order to precise their destination after ED (home, ICU, ward) and 28- and 90-days mortality after hospital admission.

Interventions

OTHERCapillary refill time and skin mottling score measurement at the admission to the emergency department

Patients who meet the inclusion criteria and none of the non-inclusion criteria will benefit from capillary refill time and skin mottling score measurement at the admission to the emergency department (ED) and followed during their hospital stay to precise the destination after ED (home, ICU, ward) and 30- and 90-days mortality after hospital admission.

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

1. Age \> 18 years 2. Skin mottling score\> 2 and/or capillary refill time \> 3secondes associated with at least one of the followings measured at the ED admission by the nurse in charge of the patient: 1. Systolic blood pressure \< 90mmHg or blood pressure decrease of 30% at least for patients with high blood pressure history 2. Heart rate \> 120 beats per minute 3. Respiratory rate \> 22 movements per minute 4. Glasgow coma scale \< 13.

Exclusion criteria

1. Age \< 18 years 2. Pregnancy 3. Serious co morbid conditions with a not to be reanimated status known at the ED admission 4. Patients with guardianship or curator

Design outcomes

Primary

Measure	Time frame	Description
Rate of ICU admission after ED.	2 days	The rate of ICU admission after ED will be monitored for each patient

Secondary

Measure	Time frame	Description
Mortality on day 30 after hospital admission	30 days	The vital status (alive or deceased) will be recorded on day 30 after hospital admission
Mortality on day 90 after hospital admission	90 days	The vital status (alive or deceased) will be recorded on day 90 after hospital admission

Countries

France

Contacts

Primary ContactRomain Jouffroy, MD

romain.jouffroy@gmail.com+33144495989

Backup ContactBenoit Vivien, MD, PhD

benoit.vivien@aphp.fr+33144492424

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026