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PRP in 2ry Spontaneous Pneumothorax

Platelet Rich Plasma in Secondary Spontaneous Pneumothorax

Status
UNKNOWN
Phases
Phase 1
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT03830645
Enrollment
40
Registered
2019-02-05
Start date
2018-11-05
Completion date
2020-12-31
Last updated
2020-06-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pneumothorax Spontaneous Secondary

Brief summary

secondary spontaneous pneumothorax patients will be enrolled ,all of them will receive PRP with different doses and schedules

Interventions

BIOLOGICALPlatelet Rich Plasma

Application of platelet rich plasma through the intercostal tube into the pleural space

Sponsors

Zagazig University
Lead SponsorOTHER_GOV

Study design

Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* COPD patients developed spontanous pneumothorax and was managed with intercostal tube insertion

Exclusion criteria

* refusal of participation

Design outcomes

Primary

MeasureTime frameDescription
Air leak assessment by Cerfolio classification of the air leak by single observerwithin 10 days after application of platelet rich plasmaContinuous:Air leak is Present throughout the respiratory cycle Inspiratory : Present during the inspiration phase of the respiratory cycle. Expiratory: Present only during the expiratory phase of the respiratory cycle Forced expiration: Present only when the patient coughs or forces exhalation
physician assessment of complete lung inflation by absence of signs of pneumothorax in chest x ray done to the patient during hospital staywithin 10 days after application of platelet rich plasmano Chest x ray signs of pneumothorax i.e no jet balck translucency or border of collapsed lung) by physician interpretation
recurrence of pneumothorax by physician interpretation of Chest x ray done to the patient in follow up visit i.e detecting jet balck translucency or border of collapsed lungone month after removal of intercostal tubeno Chest x ray signs of pneumothorax i.e no jet balck translucency or border of collapsed lung) by physician interpretation

Countries

Egypt

Contacts

Primary ContactAhmad Abbas, MD
amabbaas@zu.edu.eg201155355369
Backup ContactMohammed Walaa, MD
201002089696

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026