Mental Disorders
Conditions
Brief summary
Electroconvulsive treatment (ECT) is still actual for treatment of psychiatric symptoms. Headache is a very common symptom after this application. The investigators compare the effect of two different drugs for the treatment of headache after ECT.
Detailed description
Electroconvulsive treatment (ECT) is used as an alternative application instead of drug therapy for psychiatric symptoms. ECT application is repeated 8-12 times according to the treatment of the patient. This treatment is done in 2 or 3 days intervals. The most adverse effects of ECT are headache, memory disorders, myalgia, nausea and vomiting, cardiovascular problems. The most common seen adverse effect is headache with approximately 60% incidence. The main drugs used for the treatment of headache related to ECT are NSAIs and paracetamol. The aim of the current study is to compare the effect of paracetamol and dexketoprofen trometamol on headache treatment after ECT.
Interventions
DRUGParacetamol
The investigators apply paracetamol during a week in preoperative room 45 min before ECT
DRUGDeksketoprofen trometamol
The investigators apply paracetamol during a week in preoperative room 45 min before ECT
DRUGPlacebo
The investigators apply placebo during a week in preoperative room 45 min before ECT
Sponsors
Mustafa Kemal University
Study design
Allocation
RANDOMIZED
Intervention model
SEQUENTIAL
Primary purpose
TREATMENT
Masking
TRIPLE (Subject, Caregiver, Investigator)
Intervention model description
Each drug for one week
Eligibility
Sex/Gender
ALL
Age
18 Years to 80 Years
Healthy volunteers
No
Inclusion criteria
* All patients who were admitted for ECT and gave informed written consent were included in the study.
Exclusion criteria
*
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Headache (Visual Analogue Scale 0-10) | Postoperative 2. hour, 4. hour, 6. hour (up to six hours after intervention) | Headache (VAS) change is being assessed in three different time frames after ECT |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Additive analgesic-antiemetic consumption | Postoperative 2. hour, 4. hour, 6. hour (up to six hours after intervention) | If VAS ≥ 4, then diclofenac sodium im is given- If nausea-vomiting occurs, ondansetrone 4mg iv is given.The numbers of given drugs will be recorded in each interval. |
| Adverse effects (Nausea-Vomiting, bradycardia, hypotension) | Postoperative 2. hour, 4. hour, 6. hour (up to six hours after intervention) | Number of adverse efffects will be recorded in each interval. |
Countries
Turkey (Türkiye)
Contacts
Primary ContactCagla Buket Akkurt, Prof
Outcome results
None listed