Cataract Bilateral Nos, Hyperalgesia
Conditions
Brief summary
To evaluate the effect of oral gabapentin premedication on hyperalgesia in elderly patients undergoing staged bilateral cataract operations under monitored anesthesia care
Detailed description
It has been reported that patients with bilateral cataract complained more pain and discomfort during the second consecutive eye surgery compared to the first eye surgery. Gabapentin is an anticonvulsant drug, which has been extended the use to perioperative analgesia, and anxiolysis. Therefore, the investigators conducted this randomized, controlled study to evaluate the effects of gabapentin premedication on patients' subjective sensations, including intraoperative anxiety, perceptions of pain, and light sensitivity, in the second cataract operations.
Interventions
DRUGGabapentin
Patients receive gabapentin 100mg orally for 3 times a day during the period of first and second cataract operations
Sponsors
Seoul National University Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
DOUBLE (Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
60 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* patients aged over 60 years, who undergoing staged bilateral cataract operations under monitored anesthesia care * ASA physical status of I, II, and III
Exclusion criteria
* undergoing other eye operations together besides cataract operation * patients with creatinin clearance lower than 30ml/min * patients with CNS inhibitors medication * patients with previous gabapentin medication * pregnancy
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Pain perception | during the operation | intraoperative pain perception evaluated by VAS in first and second cataract surgery |
Countries
South Korea
Outcome results
None listed