Electronic Cigarette Use
Conditions
Brief summary
The purpose of this research study is to find out about ethanol-containing e-cigarettes impact ethanol breath tests, field sobriety tests, or other tests of sobriety. Ethanol is a common part of e-cigarette liquids.
Interventions
OTHERE-cigarette liquid with ethanol, 1 puff
E-cigarette liquid with ethanol, 1 puff
OTHERE-cigarette liquid without ethanol, 1 puff
E-cigarette liquid without ethanol, 1 puff
OTHERE-cigarette liquid with ethanol, 10 puffs
E-cigarette liquid with ethanol, 10 puffs
OTHERE-cigarette liquid without ethanol, 10 puffs
E-cigarette liquid without ethanol, 10 puffs
Sponsors
U.S. Department of Justice
Virginia Commonwealth University
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
BASIC_SCIENCE
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
ALL
Age
21 Years to 65 Years
Healthy volunteers
Yes
Inclusion criteria
* Individuals must be e-cigarette users who are 21-65, willing to provide informed consent, attend the lab sessions as needed. Participants must agree to use designated products according to study protocol.
Exclusion criteria
* Women will be excluded if they are breast-feeding or test positive for pregnancy (by urinalysis) at screening. * Some study details about the eligibility criteria are purposely omitted at this time to preserve scientific integrity. Full details will be posted at the conclusion of the study.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Preliminary breath test for ethanol | Conducted before and after the e-cigarette is used by the participant, at multiple time points (change from baseline reading at 27, 35, 40, 45, and 56 minutes after e-cigarette use) | Initial type of breath test used (gives percent blood alcohol concentration) |
| Evidentiary breath test for ethanol | Conducted before and after the e-cigarette is used by the participant, at multiple time points (change from baseline at 29, 37, 42, 47, and 58 minutes after e-cigarette use) | Secondary type of breath test used (gives percent blood alcohol concentration) |
| Standard Field Sobriety Test | Conducted before and after the e-cigarette is used by the participant, at multiple time points (change from baseline at 30 and 49 minutes after e-cigarette use) | Test used to determine sobriety |
Other
| Measure | Time frame | Description |
|---|---|---|
| Direct Effects of Vaping Questionnaire | Administered after e-cigarette use (at 39 minutes after e-cigarette use) | Questionnaire that asks participants about their vaping experience (10 questions, each scored from 0 - 100) |
| Biphasic Alcohol Effects Scale | Conducted before and after the e-cigarette is used by the participant (change from baseline at 39 and 54 minutes after e-cigarette use) | Questionnaire that asks participants about effects associated with alcohol use (14 questions, each scored from 0 - 10) |
| General Labeled Magnitude Scale | Administered after e-cigarette use (at 39 minutes after e-cigarette use) | Questionnaire that asks participants about flavor sensation, harshness/irritancy, and throat hit of the e-cigarette (3 questions, each scored from 0 - 100) |
Countries
United States
Outcome results
None listed