Hyperbilirubinemia, Neonatal, Quality Improvement
Conditions
Keywords
Quality improvement, Hyperbilirubinemia, screening, follow-up
Brief summary
Eight hospitals in China will participate in the study, which aims to decrease the incidence of severe hyperbilirubinemia.
Detailed description
Through a prospective cohort study of healthy term and near-term infants, the study tries to truly reflect the epidemiology, intervention status, and outcomes of neonatal hyperbilirubinemia and the cost. Hopefully, by improving the quality of management of neonatal jaundice,we can explore and obtain a healthy term and near-term jaundice management model suitable for China's national condition, which can eventually reduce the incidence rate of neonatal severe hyperbilirubinemia and bilirubin encephalopathy.
Interventions
BEHAVIORALQuality improvement of management of neonatal jaundice
During the Intervention phase and Sustainability phase ,The hospitals will receive training of multiple evidence based quality improvement methods.
Sponsors
JiLin Women and Children Health Hospital
Shandong Provincial Hospital
Shan Dong Qian Fo Shan Hospital
Shan Dong Liao Cheng Hospital
Guangxi Maternal and Child Health Hospital
Northwest Women's and Children's Hospital, Xi'an, Shaanxi
Yin Chuan Maternity and Child Health Hospital
Nanjing Medical University
Study design
Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
HEALTH_SERVICES_RESEARCH
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
ALL
Age
1 Days to 28 Days
Healthy volunteers
No
Inclusion criteria
term or near-term neonates with gestational age ≥35w and birth weight ≥2000g.
Exclusion criteria
Infants admitted to a higher level of intervention before discharge.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The incidence of bilirubin encephalopathy | 18 months |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| The incidence of severe hyperbilirubinemia | 18 months | Severe hyperbilirubinemia:total serum bilirubin more than 20mg/dL |
| The rate of lost to follow-up | 18 months | The rate of lost to follow-up for jaundice after discharge from well-baby nursery |
| The incidence of adverse neurological outcomes in patients with severe hyperbilirubinemia | 42 months | Patients with severe hyperbilirubinemia from 11 hospitals will be followed to investigate their neurological outcomes until 24 months after birth |
| Medical costs in patients with severe hyperbilirubinemia | 18 months | To compare the medical costs in patients with severe hyperbilirubinemia from 3 phases of quality improvement. |
Countries
China
Outcome results
None listed