Cardiorespiratory Fitness, Diabetes Mellitus, Type 2, Exercise Test, Inflammation, Prediabetic State
Conditions
Keywords
prediabetes, type 2 diabetes, cardiorespiratory fitness, pulmonary functions, functional capacity, exercise capacity
Brief summary
The aim of this study to investigate and compare cardiorespiratory fitness (CRF) parameters of prediabetic, type 2 diabetic and healthy individuals. CRF assessed with cardiopulmonary exercise test (CPET) which is gold standard measure of CRF. Pulmonary functions, inflammation, disease specific parameters such as HbA1c, fasting plasma glucose etc affect CRF in prediabetic and type 2 diabetics.All parameters examine in this study.
Detailed description
This study will be participated with Type 2 diabetic,prediabetic and healthy patients. Patients' laboratory values, pulmonary function test, respiratory muscle strength, exercise capacity, physical activity level, quality of life, cardiorespiratory fitness levels will assess and record. Pulmonary function test will be assesed with CPET system, respiratory muscle strength will be evaluated with mouth pressure. Exercise capacity will be evaluated using six minute walking test, incremental shuttle walk test. And cardiorespiratory fitness will assess CPET system. Physical activity level will be evaluated trial accelerometer and International Physical Activity Questionnaire.
Interventions
DIAGNOSTIC_TESTCardiorespiratory Fitness
Maximal symptom limited cardiopulmonary exercise test used assessment of cardiorespiratory fitness. For pulmonary function spirometry test and maximal respiratory pressures assessed.
Sponsors
Hacettepe University
Study design
Observational model
OTHER
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
Yes
Inclusion criteria
* Cooperation, * No assistance for Ambulation, * Body Mass Index\<40 * Diagnose of prediabetes/type 2 diabetes and health
Exclusion criteria
* Any cardiac problems, * Uncontrolled hypertension, * Any neurologic disease, * Uncontrolled diabetes, * Any orthopedic disease impairs walking, balance * Any respiratory disease affects cardiorespiratory fitness
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Cardiorespiratory fitness | November 2018-August 2019 | Refers to the ability of the circulatory and respiratory systems to supply oxygen to skeletal muscles during sustained physical exercise. It will be evaluated with Cardiopulmonary Exercise Test (CPET,CPX) System |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Functional Exercise Capacity | December 2018-August 2019 | 6 Minutes Walk Test's distance, meters |
| Pulmonary functions | December 2018-August 209 | Forced expiratory volume in first second (FEV1) |
| Respiratory Muscle Strength | December 2018-August 2019 | Mouth pressures; maximal inspiratory and expiratory pressure |
| Maximal Exercise Capacity | December 2018-August 2019 | İncremental Shuttle Walk Test |
| Physical Activity Level | December 2018-August 2019 | Accelerometer |
Countries
Turkey (Türkiye)
Outcome results
None listed