Skip to content

Pupillometry : Predictive Indicator in External Ventricular Drain Clamping ?

Pupillometry : Predictive Indicator in External Ventricular Drain Clamping ?

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT03823430
Acronym
CLAMP
Enrollment
100
Registered
2019-01-30
Start date
2018-07-11
Completion date
2021-03-11
Last updated
2022-02-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Brain Damage, External Ventricular Drain, Hydrocephalus

Brief summary

Pupillar diameter variation to predict success or failure of external ventricular derivation clamping. Pupillometry utilisation as a diagnostic tool in external ventricular clamping test in neurological ICU should improve patients care in several ways : * earlier use of ventriculo-peritoneal or ventriculo-atrial shunts to shorten the external ventricular treatment duration and thus reduce risks of infection and hospital stay duration * limit the medical imagery prescription and radiation exposition * avoid neurological deterioration linked to the external ventricular drain clamping in case of the pupillometric parameters variation would be earlier than clinical signs

Interventions

DIAGNOSTIC_TESTPupillometry

Pupillar diameter variation measurement

Sponsors

Association Pro-arte
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Neurologic ICU hospitalization * Traumatic brain injury * External ventricular drain

Exclusion criteria

* Legal protection * refusal * therapeutics limitation * craniectomy * pupillar anomaly

Design outcomes

Primary

MeasureTime frameDescription
Pupillar diameter variation to predict success or failure of external ventricular clamping24 hours after clampingPupillar diameter variation twenty-four hours after external ventricular drain clamping

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026