Skip to content

Incentivizing Buprenorphine-Naloxone Initiation in Emergency Departments

Incentivizing Buprenorphine-Naloxone Initiation in Emergency Departments

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT03821103
Enrollment
104
Registered
2019-01-29
Start date
2019-02-06
Completion date
2020-02-29
Last updated
2020-03-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Opioid Use

Brief summary

This study seeks to test standard and behavioral economic-enhanced training strategies to bolster first-time Emergency Department-initiated buprenorphine-naloxone administration among Emergency Department providers.

Detailed description

Philadelphia is experiencing a significant opioid crisis. Through this novel pilot study, critical training about opioid use disorder and medication-assisted treatment with buprenorphine-naloxone will be provided to emergency providers and changes in clinical practice will be incentivized in order to optimize treatment engagement for patients with opioid use disorder in the Emergency Department. Participants will be invited to participate in a brief in-person training session, will receive a pre- and post-session knowledge and attitude assessment, and will be invited to self-report first-time buprenorphine-naloxone Emergency Department administration within the 3 month study period. Participants will be randomized to one of two arms: standard training arm and behavioral economic enhanced arm. The standard training arm will receive the aforementioned intervention. The behavioral economic enhanced arm will additionally receive an opt-out invitation, loss-framed incentivization, and weekly tailored text message-based reminders. Endpoints of interest include retained knowledge and change in provider attitudes regarding Emergency department buprenorphine-naloxone administration and treatment following training and again at 3 months, and first-time Emergency department administration of buprenorphine-naloxone.

Interventions

BEHAVIORALTraining

The training includes of (1) in-person training with pre- and post-session knowledge and attitude assessment, (2) three month post-session knowledge and attitude assessment and (3) self-report of first-time buprenorphine-naloxone Emergency Department (ED) administration within 3 month study period

BEHAVIORALBehavioral economic enhanced arm

Behavioral economic enhancement includes an opt-out invitation, loss-framed incentivization, weekly tailored text based reminders

Sponsors

American College of Medical Toxicology
CollaboratorOTHER
Blue Cross Blue Shield
CollaboratorOTHER
University of Pennsylvania
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
HEALTH_SERVICES_RESEARCH
Masking
DOUBLE (Investigator, Outcomes Assessor)

Eligibility

Sex/Gender
ALL
Healthy volunteers
No

Inclusion criteria

* Residents and Advanced Practice Providers and attending clinicians working in emergency departments in Pennsylvania.

Exclusion criteria

\-

Design outcomes

Primary

MeasureTime frameDescription
Change in Emergency Department initiated buprenorphine-naloxone treatmentOne yearMeasuring number of providers who have initiated at least one first dose of buprenorphine-naloxone

Secondary

MeasureTime frameDescription
Training AttendanceFirst weekMeasure the number of clinicians who attend the training with the incentive.
Change in attitude about buprenorphine-naloxone QuestionaireThree monthsThe scale is not a validated tool. It is a construct to measure attitudes about buprenorphine-naloxone. It is a Likert scale 1-5, 1 being strongly disagree and 5 being strongly agree. Higher values signify more favorable outcomes.

Other

MeasureTime frameDescription
Retained knowledge of buprenorphine-naloxone treatment QuestionaireThree monthsCompare retention of knowledge and assessment from before and after the training in the two arms.The scale is not a validated tool. It is a construct of questions to measure retained knowledge about buprenorphine-naloxone initiation. The scale is a percentage of questions answered correctly. Minimum score is 0% and maximum score is 100%. Higher values signify more favorable outcomes.

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 12, 2026