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Whipple Procedure: A 5-year Clinical Experience in Tertiary Care Center

Whipple Procedure: A 5-year Clinical Experience in Tertiary Care Center

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT03820583
Enrollment
57
Registered
2019-01-29
Start date
2014-01-01
Completion date
2018-12-31
Last updated
2019-01-31

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Whipple Procedure

Keywords

Whipple procedure, pancreatic carcinoma, biliary stenting,

Brief summary

The study was conducted in tertiary care hospital of Lahore. Patient undergoing Whipple procedure were studied by compiling demographic details of the patients, common presenting symptoms, various indications for Whipple's procedure, the cofactors which affect the procedures outcome and morbidity and mortality of the patients.

Detailed description

This study was performed by collecting data through predesigned questionnaire about patients undergoing Whipple's procedure from operation theatres and medical record section. Those patients, whose tumor was unresectable and undergone palliative surgical procedures were excluded from the study.

Interventions

Patients underwent Whipple procedure for pancreatic tumors. The procedure commenced with rooftop incision. then layers of abdomen dissected to reach the peritoneum. Then Duodenum dissected out along with pancreas and common bile duct. After rescetion of these structures the anatomy of the tract restored with three anastomosis namely pancreaticojejunostomy, gastrojejunostomy and choledochojejunostomy/hepaticojejunostomy.

Sponsors

Services Hospital, Lahore
Lead SponsorOTHER_GOV

Study design

Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE

Intervention model description

Patients undergoing Whipple procedure due to pancreatic tumor were included in the study

Eligibility

Sex/Gender
ALL
Age
20 Years to 70 Years
Healthy volunteers
No

Inclusion criteria

* patients of both sexes with age ranging from 20 years to 70 years * patients with pancreatic tumors * patients with adequate cardiorespiratory reserves to be fit for prolong general anesthesia

Exclusion criteria

* unresectable tumors * unfit for surgery

Design outcomes

Primary

MeasureTime frameDescription
Percentage of patients developing pancreatic fistula4 weeksPercentage of patients developing pancreatic fistula (pancreatic juice collected in drain rich in amylase) after Whipple procedure Enteric leak postoperative complications like pancreatic fistula, anastomotic leakage, hemorrhage, wound infection,mortality
Percentage of patients developing hemorrhage2 weeksPercentage of patients developing hemorrhage after Whipple procedure
Percentage of patients developing wound infection4 weeksPercentage of patients developing wound infection after Whipple procedure
Mortality rate6 weeksMortality of patients undergoing Whipple surgery

Countries

Pakistan

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026