Myopia, Progressive
Conditions
Keywords
Myopia, Myopia control
Brief summary
Diurnal variations in the thickness of the choroid have been reported in the literature, and, more recently, the role of the choroid has been studied with respect to its role in myopia (near-sightedness) progression.
Detailed description
Diurnal variations in the thickness of the choroid have been reported in the literature , and, more recently, the role of the choroid has been studied with respect to its role in myopia (near-sightedness) progression. SightGlass Vision, Inc is conducting a multi-site, randomized, controlled, interventional study to confirm the efficacy and safety of spectacle lenses designed to inhibit the progression of myopia by reducing image contrast in peripheral vision. CORE is participating as a clinical site in this three year study which aims to compare changes in ocular length and cycloplegic auto-refraction in children randomised to wear one of either two test or one control spectacle lens designs; the CPRO-1802-001 (Cypress\_SG) study. The sponsor is interested in conducting choroidal thickness measurements only at CORE's site by inviting those participants who have already been found eligible for the CPRO-1802-001 study to participate in this parallel study.
Interventions
Spectacle lens to control progression of myopia
Sponsors
SightGlass Vision, Inc.
University of Waterloo
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
6 Years to 10 Years
Healthy volunteers
Yes
Inclusion criteria
* Participating in the CPRO-1802-001 (Cypress\_SG) study at CORE * Read and signed an Assent and their parent/guardian has signed an information consent letter
Exclusion criteria
* Transient health condition which may affect the eye(s) (e.g. a common cold, active allergies, fatigue, etc;)
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Choroidal thickness | 3 years | Measurement of choroidal thickness by Triton optical coherence tomographer (OCT), including post-imaging analysis |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Visual field | 3 years | Assessment of visual field to determine if changes in peripheral visual function by Humphrey Visual Field Analyzer |
Countries
Canada
Contacts
PRINCIPAL_INVESTIGATORLyndon Jones, PhD, FCOptom
Centre for Ocular Research & Education, Canada
STUDY_DIRECTORJill Woods, BSc, MCOptom
Centre for Ocular Research & Education, Canada
Outcome results
None listed