Skip to content

Chronic Ankle Instability Diagnostic Tests Determining Underlying Deficits

Biomechanical Analysis, Complementary Examinations and Rehabilitative Management of Chronic Ankle Instability

Status
Terminated
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT03818438
Acronym
CAIDiag
Enrollment
4
Registered
2019-01-28
Start date
2019-10-24
Completion date
2021-10-25
Last updated
2022-05-31

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ankle Dislocation, Chronic Ankle Instability

Keywords

Chronic instability, Strength, Proprioception, Rehabilitation, Ankle, Balance

Brief summary

Chronic ankle instability is a common condition in the active adult population and characterized by the occurrence of repeated giving way and/or recurrent ankle sprains. Multiple underlying deficits have been proposed, among which ankle muscle strength deficits, proprioception deficits, ( static and dynamic balance disorders, and articular laxity. Unfortunately, no consensus exists on which clinical tests should be realized to determine if one of these underlying deficits is predominant and as a result could guide the rehabilitation process. The study hypothesis is that people with chronic ankle instability might be heterogenous and could be divided in different subgroups as a function of underlying deficits. Therefore, this study aims to evaluate the capacity of different clinical tests to differentiate people with chronic ankle instability from healthy people as well as between each other.

Interventions

None listed

Sponsors

Ministry of Health, France
CollaboratorOTHER_GOV
University Hospital, Lille
Lead SponsorOTHER

Study design

Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to 45 Years
Healthy volunteers
Yes

Inclusion criteria

* Case subject : at least one initial lateral ankle sprain more than 12 months before inclusion * Case subject : at least one residual symptom among (1) giving way, (2) sensation of instability, (3) recurrent ankle sprain. This item is confirmed by a score inferior than 24 on the Chronic Ankle Instability Tool (CAIT) * Case subject : Impact on activities of daily living and sport, confirmed by a score of less than 90% on the Foot and Ankle Ability Measure (FAAM) and less than 80% on FAAM-- - -- Control subject : matched by age and sex to case subjects

Exclusion criteria

* Surgery of one of the lower limbs less than 3 years ago * Presence of heavy pain (EVA \> 8) regardless of its origin * Acute lateral ankle sprain less than 4 months before inclusion * Neurological disorders of any kind * Medical treatment (drugs) interfering with muscle tone, balance and proprioception disorders * Pregnant or breastfeeding women * Body mass index \> 30 * Bilateral chronic ankle instability

Design outcomes

Primary

MeasureTime frameDescription
Strength tests (both ankles tested)BaselineIsokinetic strength tests (both ankles tested) : * Plantar flexor peak torque (Nm) * Dorsiflexor peak torque (Nm) * Inversion peak torque (Nm) * Eversion Peak torque (Nm)
Static balance testsBaselineStatic balance tests ( DLS and SLS (both ankles tested) ; Stabilometry) are composite measure * Centre of Pressure (COP) displacement (mm) ; * COP velocity (mm/s) * COP area (mm²) * COP time-to-boundary (TTB) (s) * Number of foot lifts (integer)
the Star Excursion Balance Test (SEBT)BaselineDynamic balance test : SEBT (both ankles tested) : are composite measure * Distance reached in anterior direction (% leg length) * Distance reached in posteromedial direction (% leg length) * Distance reached in posterolateral direction (% leg length) * Time used to reach (s) * COP displacement (mm) * COP velocity (s) * COP area (mm²) * COP time-to-boundary (TTB) (s)
Hop testsBaselineHop tests (both ankles tested) : SLHD et SH ; are composite measure * Distance reached (m) * Max inversion angle ankle joint (°) * Max internal rotation angle ankle joint (°) * Max vertical Ground Reaction Force (GRF) at landing (N) * Max lateral GRF (N) * Time used to complete 10 hops (s)

Secondary

MeasureTime frameDescription
Intra-class correlation coefficients (reproducibility test-retest)Baseline and 1-4 weeks after baselineIntra-class correlation coefficients (reproducibility test-retest) calculated on the subset of the parameters identified by the main analysis. Recyclability of the functional clinical tests : Normality testing /Sample comparison

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026