Muscle Weakness, Fatigue, Multiple Sclerosis, Deglutition Disorders, Exertion; Excess
Conditions
Brief summary
Multiple Sclerosis (MS) patients with subjective dysphagia will be tested for tongue strength fatigue using a strictly defined fatigue paradigm. A maximum of 40 sets will be performed, each set consisting of 5 repetitions of 80% of maximum isometric pressure (MIP) at the anterior tongue, followed by a MIP at the anterior tongue. Cut-off criteria are a MIP \<50% of the baseline MIP, pronounced subjective discomfort and/or exceeding the allocated test time of 30 minutes.
Detailed description
Eligibility is Mini-Mental State Exam-score (MMSE) \> 23, a Eating Assessment Tool-score (EAT-10) \> 3, or a Functional Oral Intake Scale-score (FOIS) \< 7, or failing the Yale Swallow Protocol.
Interventions
Using biofeedback to attain repetitions of 80% of baseline MIP.
Sponsors
Revalidatie & MS Centrum Overpelt
Thomas More Kempen
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
SCREENING
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* proven MS * subjective dysphagia
Exclusion criteria
* MMSE \< 23 * major head and neck surgery * history of cancer
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Number of successful repetitions | 30 minutes | The number of repetitions where the target force was developed. |
| Evolution of MIP during subsequent repetitions | 30 minutes | The change in MIP after each 5 repetitions. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Baseline MIP as predictor for number of repetitions | 30 minutes | Does baseline MIP predict the number of successful repetitions. |
Countries
Belgium
Contacts
Primary ContactJan Vanderwegen, MD
Outcome results
None listed