Oligohydramnios
Conditions
Keywords
oligohydroamnios, low salt diet
Brief summary
The investigators want to examine whether low salt diet can increase the amniotic fluid index in patients diagnosed with oligohydramnios and assigned for conservative management. A randomized controlled trial
Detailed description
Few studies have addressed the changes in maternal diet as affecting the composition and amount of amniotic fluid. Some articles have shown an increase in amniotic fluid volume as a result of maternal hydration during pregnancy through intravenous fluid infusions and oral fluid intake, the increase was evident in women with amniotic fluid and women with normal amniotic fluid volume. In a mechanism similar to that of liquid hydration, a low-salt diet may lead to an increase in the volume of amniotic fluid. The investigators would like to examine whether a low-salt diet in women with amniotic fluid is able to significantly increase the amount of amniotic fluid compared with a regular diet.
Interventions
OTHERlow sodium diet
included in the diet mostly low sodium food. avoid tinned or smoked, food. avoid adding salt to the food.
Sponsors
Wolfson Medical Center
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Healthy volunteers
Yes
Inclusion criteria
* Pregnant women between 24-37 weeks of gestation, single fetus, who were diagnosed with an amniotic fluid index at the 5th percentile or below, according to the current gestational age * No medical indication for immediate delivery
Exclusion criteria
* Refusal to participate in the study * A medical recommendation for delivery within two weeks of diagnosis * Fetal malformation or proof of fetal infection that known to cause oligohydramnios (eg CMV). * Premature rupture of membrane * Multiple pregnancy * Medical contraindication to the low-salt diet
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| amniotic fluid volume, assessed by ultrasound | two weeks | amniotic fluid volume after two weeks |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| gestational age at birth | up to 18 weeks (until delivery) | — |
| induction of labor | up to 18 weeks (until delivery) | The percentage of pregnant women who underwent birth induction |
| labor type | up to 18 weeks (until delivery) | Cesarean section, vaginal birth or vaginal birth |
| Pregnancy and childbirth complications | up to 18 weeks (until delivery) | obstetrics complications and neonatal complications |
Countries
Israel
Contacts
Primary ContactMichal Levy, MD
Backup ContactEran Weiner, MD
Outcome results
None listed