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Inter-observer and Intra-observer Variability of the Wrinkle Test

Inter-observer and Intra-observer Variability of the Wrinkle Test and the Optimum Time Need for the Test. Pilot Study

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT03813758
Enrollment
50
Registered
2019-01-23
Start date
2019-09-15
Completion date
2020-01-01
Last updated
2019-08-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Wrinkle Test

Brief summary

Skin wrinkling of the fingers following immersion in warm water depends on intact sympathetic innervation. It is abolished by lesions affecting both central and peripheral sympathetic pathways. It affords a simple and reliable clinical test of sympathetic function.

Detailed description

Fingertip skin wrinkling after prolonged immersion in water is a well-recognized phenomenon, whereas a denervated digit does not exhibit normal skin wrinkling while a finger with a regenerated or repaired nerve shows at least partial reappearance of wrinkling. This is the basis for the bedside immersion-wrinkling test of autonomic digital nerve function. The exact mechanism of fingertip skin wrinkling is still subject to controversy. the purpose of this study is to examine the Inter-observer and Intra-observer Variability of the Wrinkle Test.

Interventions

DIAGNOSTIC_TESTwrinkle test

soaking in 40 deg water for 40 min. every 10 min the hand will be photo

Sponsors

HaEmek Medical Center, Israel
Lead SponsorOTHER

Study design

Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
2 Years to 100 Years
Healthy volunteers
Yes

Inclusion criteria

* patients after suture of full cut of digital nerve

Exclusion criteria

* other nerve injury

Design outcomes

Primary

MeasureTime frameDescription
wrinkle test40 minwrinkle of the skin in the finger compaared to the finger witout digital nerve injury

Countries

Israel

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026