Lactated Ringer's and PlasmaLyte in Critically Ill Adults

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT03813563

Enrollment

12000

Registered

2019-01-23

Start date

2018-01-13

Completion date

2019-02-28

Last updated

2019-01-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Critical Illness

Brief summary

In recent years, there has been a large amount of literature reports that normal saline can increase the incidence of renal injury in critically ill patients compared with balanced salt solution.However, no studies have compared the effects of different types of balanced salt solutions on the incidence of renal injury.

Interventions

DRUGRL

lactated Ringer's

DRUGPLA

PlasmaLyte

Study design

Observational model

COHORT

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* All patients admitted to ICU

Exclusion criteria

* Patients \<18 year old when admission * Patients who stay less than 24 hours in ICU * Patients who do not sufficient data for further analysis * Readmission patients during the study period

Design outcomes

Primary

Measure	Time frame	Description
The incidence of acute kidney injury	from admission to 28 days	The incidence of acute kidney injury

Secondary

Measure	Time frame	Description
the incidency of CRRT events	from admission to 28 days	the incidency of CRRT events
the ventilation free days	from admission to 28 days	the ventilation free days
the vasopressure free days	from admission to 28 days	the vasopressure free days

Countries

China

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026