Atherosclerosis, Coronary, Cardiovascular Diseases, Rheumatoid Arthritis
Conditions
Brief summary
Cardiovascular disease is a leading cause for morbidity and mortality in general population. The incidence of cardiovascular disease and their poor outcome is well documented in a broad spectrum of connective tissue diseases, especially in rheumatoid arthritis (RA). The risk of incident CVD is increased by 48% in patients with RA compared to the general population. RA is associated with 50% increase in the mortality in patients with cardiovascular disease (CVD). One reason is the more frequent cardiovascular risk factors in RA patients compared with the general population. Patients with RA have a high risk of premature cardiovascular disease (CVD). The aim of the present study is to assess whether there are non-invasive measures that might predict arteriosclerosis in RA patients.
Interventions
None listed
Sponsors
Ziv Hospital
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 70 Years
Healthy volunteers
No
Inclusion criteria
1. 18-70 years old (except for women till 75 years old) 2. Absence of established CVD: * Myocardial Infarction p/h * PCI with balloon and/or stent * Intermittent claudication * PAD / intervention * CAS /intervention 3. Signed informed consent form 4. Documented diagnosis of rheumatoid arthritis
Exclusion criteria
1. Known CVD 2. Pregnancy
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Cardiovascular disease risks in patient with theumatoid arthritis | 6 months | Prediction of cardiovascular risks and proposed preventive treatment |
Contacts
Primary ContactNaaem Simaan, Dr
Backup ContactKarine Beiruti, PhD
Outcome results
None listed