Liver Resection
Conditions
Keywords
three-dimensional reconstruction, fluorescence, indocyanine green, liver resection, navigation surgery
Brief summary
The aim of this study was to evaluate the feasibility and efficacy of a novel real-time navigation way for laparoscope liver resection, which was fused images comprising 3D imaging and indocyanine green Fluorescence imaging (fusion IGFI).
Detailed description
During liver resection, surgeons cannot completely view the intraparenchymal structure. Although a fluorescent imaging technique using indocyanine green has recently been developed for hepatobiliary surgery, limitations in its application for real-time navigation persist. A nove augmented reality surgery navigation system (ARSNS) can be combined with indocyanine green Fluorescence imaging to guide the surgery real-time.
Interventions
DEVICELaparoscopic surgical navigation system
We will use this navigation system to guide de liver resection.
DRUGIndocyanine Green
ICG was administered 24 hours before the operation or intravenously after clamping the Glissonian sheaths flowing in the cancer-bearing hepatic segment, or directly into the portal branches supplying blood flow to the tumor-bearing hepatic segment, after puncturing of the target segments under intraoperative ultrasonography guidance.
Sponsors
Zhujiang Hospital
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 70 Years
Healthy volunteers
No
Inclusion criteria
1. 18 years≤ Age ≤70 years 2. Compling with the diagnosis criteria of complex hepatic carcinoma. 3. Primary hepatic carcinoma without intrahepatic or extrahepatic extensive cancer metastasis, the metastatic hepatic carcinoma whose primary focal has been controlled 4. Preoperative liver function is Child - Pugh grade A or B. 5. The patients are volunteered for the study.
Exclusion criteria
1. Patients with mental illness. 2. Patients can't tolerate the operation owe to a variety of basic diseases (such as severe cardiopulmonary insufficiency, renal insufficiency, cachexia and blood system diseases, etc.) 3. The patients refused to take part in the study. 4. There are other co-existed malignant tumors. 5. Benign liver diseases. 6. Indocyanine green allergy
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Liver resection navigation success rate | intraoperative | Whether this technique successfully displayed the pre-resection line during the surgery were recorded. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Postoperative complication rate | 3 months | The Postoperative complications were recorded. |
| Operative outcomes | intraoperative | Operative outcomes such as operative time, estimated blood loss and blood transfusion were recorded. |
Countries
China
Contacts
Primary ContactFang Chihua, M.D.;Ph.D
Outcome results
None listed