Parkinson Disease
Conditions
Keywords
movement disorders, light therapy, motor aspects
Brief summary
This study aimed to assess the effects of transcranial photobiomodulation in patients with Parkinson's disease (PD).
Detailed description
Thirty-five patients with idiopathic PD were randomly assigned to a photobiomodulation (n=17, \[mean±SD\] 72±7 years) or sham group (n=18, 70±8 years) during 9 weeks (2 sessions/week). The primary endpoint was the motor portion of the Movement Disorders Society-United PD Rating Scale. Secondary endpoints were the Scales for Outcomes in PD, static posturography, walking ability (ten-meter walk test \[TMWT\]) and functional mobility (timed up and go \[TUG\] test).
Interventions
Photobiomodulation was administered using red light-emitting diodes (LEDs) with a 670-nm wavelength (which has proven to penetrate the skull)
Sponsors
University of Oviedo
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
ALL
Healthy volunteers
No
Inclusion criteria
* Having been diagnosed with idiopathic PD. * Stage 1-2 on the Hoehn and Yahr Scale. * Having no neurological condition other than PD. * Being able to stand for 2 minutes and walk 10 meters without assistance. * Having no severe dyskinesias or ON-OFF phases.
Exclusion criteria
\- Do not follow inclusion criteria.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| The motor portion of the MDS-UPDRS. | 9 weeks | The motor portion (part III) Movement Disorders Society-Unified PD Rating Scale. It assesses the motor signs of Parkinson´s disease (minimum and maximum score is 0 and 76 points respectively -the higher score, the higher movement disorder and vice versa-). |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Motor function | 9 weeks | The Spanish-validated version of the Short Parkinson's Evaluation Scale (SPES)/Scales for Outcomes in PD (SCOPA). It measures the Parkinson´s disease patients motor function (minimum and maximum score is 0 and 63 points respectively -the higher score, the worse motor function and vice versa-). |
| Static posturography | 9 weeks | The centre of pressure (CoP) parameters (these CoP parameters; Length in mm, Area in mm2 and Speed in m/s are combined to report the static posturography). |
| Walking speed | 9 weeks | Ten-meter walk test |
| TUG | 9 weeks | Timed up and go test |
Countries
Spain
Outcome results
None listed