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Prevalence and Risk Factors Nocturnal Polyuria in Female OAB

Prevalence and Risk Factors of Nocturnal Polyuria in Female Overactive Bladder Syndrome

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT03810027
Enrollment
1071
Registered
2019-01-18
Start date
2009-07-01
Completion date
2018-01-31
Last updated
2019-01-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Nocturia

Keywords

Nocturnal polyuria, Overactive bladder

Brief summary

Nocturnal polyuria may decrease the treatment efficacy of overactive bladder syndrome (OAB); and adjuvant medication, such as desmopressin, may be needed for the treatment of nocturnal polyuria. The knowledge of prevalence and risk factors of nocturnal polyuria might be important for the treatment of OAB. Thus, our aim is to describe the prevalence and risk factors of nocturnal polyuria in women with OAB.

Detailed description

Between July 2009 and January 2018, all women with OAB visiting a medical center for evaluation were reviewed. The classification of OAB-wet or OAB-dry is based on the record of the three-day bladder diary of each patient. The diagnosis of OAB in each patient was based on the presence of at least one episode of urgency in her three-day bladder diary and with the absence of stress urinary incontinence. The presence of at least one episode of urgency associated incontinence was defined to be OAB-wet, otherwise, OAB-dry. Nocturnal polyuria was defined when the proportion of nighttime voided volume over 24-hour voided volume was greater than 33% for ≥65-year-old women, and when the proportion of nighttime voided volume over 24-hour voided volume was greater than 20% for \<65-year-old women.

Interventions

DIAGNOSTIC_TESTBladder diary

3-day bladder diary

Sponsors

National Taiwan University Hospital
Lead SponsorOTHER

Study design

Observational model
CASE_ONLY
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
FEMALE
Age
20 Years to No maximum
Healthy volunteers
No

Inclusion criteria

1. More than 20-year-old 2. Female 3. Diagnosed with overactive bladder

Exclusion criteria

1. Younger than 20-year-old 2. Pregnant or planned to be pregnant

Design outcomes

Primary

MeasureTime frameDescription
Nocturnal polyuriaBetween July 2009 and January 2018Nocturnal polyuria was defined when the proportion of nighttime voided volume over 24-hour voided volume was greater than 33% for ≥65 year-old women, and when the proportion of nighttime voided volume over 24-hour voided volume was greater than 20% for \<65 year-old women.

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026