Chronic Periodontitis
Conditions
Brief summary
The present study aimed to assess the adjunctive use of Hyaluronic acid with scaling & root planing (SRP) in patients with chronic periodontitis & diabetes mellitus type 2.
Detailed description
Thirty subjects with chronic periodontitis & diabetes mellitus type 2 were included in this randomized clinical trial. These subjects were randomly allocated into test & control equal groups. The test group comprised fifteen patients who received SRP with subgingival application of Hyaluronic acid as an adjunct. The control group included fifteen patients who received SRP alone. Plaque index (PI), gingival index (GI), probing depth (PD) & clinical attachment level (CAL) were measured & documented at baseline, 6 weeks & 12 weeks intervals.
Interventions
PROCEDUREPeriodontal treatment with Hyaluronic acid associated with SRP
In addition to SRP, patients in the test group received adjunct subgingival application of hyaluronic acid in all selected periodontal pockets.
PROCEDUREScaling & root planning alone
Patients received full-mouth supra- & sub-gingival SRP with the use of ultrasonic device & periodontal universal & Gracey curettes under local anesthesia.
Sponsors
Cairo University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
38 Months to 56 Months
Healthy volunteers
No
Inclusion criteria
* Patients with chronic periodontitis and type 2 diabetes mellitus * Minimum of 20 teeth * Clinical attachment level (CAL) ≥ 3 mm * Probing depth (PD) ≥ 4 mm.
Exclusion criteria
* Pregnant females * Smokers
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Gain in clinical attachment level | 12 weeks | Gain in clinical attachment level will be measured in millimeter by William's graduated periodontal probe |
Countries
Egypt
Outcome results
None listed