Is it Possible to Replace Fentanyl in Anesthesia for Minor Procedures?

Is it Possible to Replace Fentanyl by Non Narcotic Medication for Induction and Maintenance of Anesthesia in Minor Procedures?

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT03806374

Enrollment

120

Registered

2019-01-16

Start date

2018-01-02

Completion date

2018-12-10

Last updated

2019-01-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anesthesia

Keywords

fentanyl, lidocaine, ketamine, induction of anesthesia, intubation

Brief summary

To compare between fentanyl group and ketamine lidocaine group for induction of anesthesia as regards hemodynamics and smooth intubation.

Detailed description

Two groups each with 60 patients Group I anesthesia initiated by propofol, fentanyl and cisatracurium. Group II anesthesia initiated by ketamine, lidocaine, propofol and cisatracurium.

Interventions

DRUGKetamine

ketamine

DRUGPropofol

propofol

DRUGFentanyl

fentanyl

DRUGCisatracurium

cisatracurium

DRUGLidocaine

lidocaine

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

PREVENTION

Masking

DOUBLE (Subject, Caregiver)

Eligibility

Sex/Gender

ALL

Age

18 Years to 55 Years

Healthy volunteers

Yes

Inclusion criteria

* ASA I and II between * Age between 18-55 years * Undergoing minor surgical procedure less than an hour.

Exclusion criteria

* Patients with hypertension * Patients with Ischemic heart diseases * Patients with chronic renal or liver diseases

Design outcomes

Primary

Measure	Time frame	Description
Intubation with less hemodynamic changes	15 minutes after induction of anesthesia.	changes in blood pressure with intubation
Smooth Maintenance of anesthesia	anesthesia time	changes in blood pressure during anesthesia
less postoperative pain killers	24 hours postoperative	amount of pain killers used and timing

Countries

Egypt

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026