FindTrial
Sign In

A Postoperative Sore Throat After Thyroidectomy

The Effect of Dexmedetomidine and Remifentanil on the Postoperative Sore Throat After Thyroidectomy

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT03805568
Enrollment
74
Registered
2019-01-15
Start date
2017-07-05
Completion date
2018-07-25
Last updated
2019-01-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Post Operative Sore Throat

Keywords

postoperative sore throat, dexmedetomidine, remifentanil, thyroidectomy

Brief summary

This study was performed to compare the effect on of a postoperative sore throat between dexmedetomidine and remifentanil in patients undergoing thyroidectomy.

Interventions

DRUGdexmedetomidine infusion group

dexmedetomidine as anaesthetic adjuvant

DRUGremifentanil infusion group

remifentanil as anaesthetic adjuvant

Sponsors

Yeungnam University College of Medicine
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
TRIPLE (Subject, Investigator, Outcomes Assessor)

Eligibility

Sex/Gender
ALL
Age
20 Years to 65 Years
Healthy volunteers
No

Inclusion criteria

* Patients who scheduled primary thyroidectomy were enrolled and their physical status was American Society of Anesthesiologists (ASA) class 1 or 2

Exclusion criteria

* Patients with respiratory tract disease, previous head, and neck surgery, preexisting steroid or non-steroidal anti-inflammatory drug use, and known or suspected difficult airway

Design outcomes

Primary

MeasureTime frameDescription
incidence of postoperative sore throat at rest6 hours after surgery0=none; 1=occur
incidence of postoperative sore throat at swallowing6 hours after surgery0=none; 1=occur
severity of postoperative sore throat at rest6 hours after surgery4-point scale (0=none; 1=mild; 2=moderate; 3=severe)
severity of postoperative sore throat at swallowing6 hours after surgery4-point scale (0=none; 1=mild; 2=moderate; 3=severe)

Countries

South Korea

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026