Jaundice, Neonatal
Conditions
Keywords
nighttime light exposure ，neonatal jaundice，China
Brief summary
Make a neonatal jaundiced nomogram on Chinese jaundice data by joinning the major neonate centers all around China.
Detailed description
This was a multi-centre prospective study. All infants included were born in 8 hospitals in the southern, eastern, northern, western and central regions of mainland China in 2019. A total of 20839 transcutaneous bilirubin(TCB) measurements were performed with 2977 neonates at designated time points. The mean NTL exposure during pregnancy was respectively calculated based on each participant's residential address over the study course. The primary outcome was whether the neonate was diagnosed with hyperbilirubinemia within the first seven days of life. The effect of maternal nocturnal light exposure on neonate jaundice analyzed with lasso regression and random forest machine learning methods.
Interventions
None listed
Sponsors
Guangdong Women and Children Hospital
Study design
Observational model
OTHER
Time perspective
OTHER
Eligibility
Sex/Gender
ALL
Age
1 Days to 7 Days
Healthy volunteers
Yes
Inclusion criteria
gestational age more than 35 weeks(≥35) -
Exclusion criteria
all kinds of congenital diseases, infants with pathologic jaundice \-
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Hour-specific Transcutaneous Bilirubin Level | 1 year | make neonatal jaundiced nomogram base on the hour-specific transcutaneous bilirubin data |
| whether the neonate was diagnosed with hyperbilirubinemia within the first seven days of life | 2019 | whether the neonate was diagnosed with hyperbilirubinemia within the first seven days of life |
Countries
China
Outcome results
None listed