Neuromuscular Blockade, Neuromuscular Monitoring, Postoperative Residual Curarization
Conditions
Brief summary
The primary object of this study is, to investigate the current procedure of neuromuscular monitoring at a tertiary academic university medical center.
Detailed description
Residual neuromuscular block is known to be a significant but frequently overlooked complication after the use of neuromuscular blocking agents. Aim of this prospective, observational study is to detect the incidence and severity of residual paralysis at a tertiary academic german university medical center. Methods: All infantile patients recieving neuromuscular blocking agents are included over a 12 week observational period. At the end of the operation procedure, directly prior to tracheal extubation a train-of-four ratio was assessed quantitatively by an independet observer using the TOF Watch SX monitor. Data related to patient postoperative outcome were collected in the operating theatre, during the way to the postoperative care unit (PACU) and during the stay in the PACU: * incidence of residual paralysis * incidence of aspiration, bronchospasm, laryngospasm, oxygen desaturation, airway obstruction,
Interventions
DIAGNOSTIC_TESTAcceleromyography
At the End of Surgery, shortly before Extubation, the TOF-Ratio is measured by an independent investigator using Acceleromyography.
Sponsors
University of Regensburg
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
1 Months to 18 Years
Healthy volunteers
Yes
Inclusion criteria
* General aneasthesia with muscle relaxation * Children between 1 Month to 18 Years * Endotracheal Intubation due to surgical or diagnostical procedures
Exclusion criteria
* older than 18 years * local aneasthesia * regional aneasthesia * larynx mask * patient comes from ICU * children who are not planned to be extubated
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Residual paralysis | Directly prior to extubation | Rate of residual paralysis after extubation of the infantile patients measured by acceleromyography. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Airway obstruction | 1, 10, 30, 60 minutes after extubation | Clinical assessment of the upper airway |
| Oxygen desaturation | 1, 10, 30, 60 minutes after extubation | Measurement of the oxygen saturation by pulse oxymetry |
| Bronchospasm, laryngospasm | 1, 10, 30, 60 minutes after extubation | Clinical assessment the airway |
Countries
Germany
Outcome results
None listed