Arthralgia, Systemic Lupus Erythematosus
Conditions
Keywords
Exercise, Hand function, Quality of Life
Brief summary
A total of 240 consecutive SLE patients fulfilling the SLICC classification criteria was evaluated. Sixty two patients who met the inclusion criteria were randomly assigned to the exercise group (n=32) or the control group (n=30). Patients in the exercise group performed a program of strengthening, stretching and resistance upper limbs exercises, of 30 minutes duration daily, for 12 weeks. Performance of daily activities was evaluated with the DASH and HAQ questionnaires, grip and pinch strength with the Jamar dynamometer and pinch gauge tools respectively, dexterity with the Purdue pegboard test and the quality of life with the LUPUSQoL questionnaire at 0, 6, 12 (end of the exercise program) and 24 weeks for both groups. SLE activity and cumulative organ damage were evaluated with the SLE disease activity index 2000 (SLEDAI-2K) and SLICC/ACR-DI, respectively.
Detailed description
A total of 240 consecutive SLE patients fulfilling the SLICC classification criteria was evaluated. Sixty two patients who met the inclusion criteria \[age\>18, upper limb arthralgias, and DASH (Disabilities of the Arm, Shoulder, and Hand) questionnaire score\>10)\] were randomly assigned to the exercise group (n=32) or the control group (n=30). Patients in the exercise group performed a program of strengthening, stretching and resistance upper limbs exercises, of 30 minutes duration daily, for 12 weeks. Performance of daily activities was evaluated with the DASH and HAQ questionnaires, grip and pinch strength with the Jamar dynamometer and pinch gauge tools respectively, dexterity with the Purdue pegboard test and the quality of life with the LUPUSQoL questionnaire at 0, 6, 12 (end of the exercise program) and 24 weeks for both groups. SLE activity and cumulative organ damage were evaluated with the SLE disease activity index 2000 (SLEDAI-2K) and SLICC/ACR-DI, respectively.
Interventions
BEHAVIORALHAND EXERCISE
Sponsors
National and Kapodistrian University of Athens
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SUPPORTIVE_CARE
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* SLE patients fulfilling the SLICC classification criteria * Upper limb arthralgias * DASH score\>10 * Stable drug regimen≥3 months
Exclusion criteria
* Hand fracture or surgery in last 6 months * Physiotherapy program in last month
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| change of DASH questionnaire | Baseline, 6, 12, 24 weeks | Hand function was measured with DASH Questionnaire |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| change of HAQ questionnaire | Baseline, 6, 12, 24 weeks | Hand function was measured with HAQ Questionnaire |
| change of Grip strength | Baseline, 6, 12, 24 weeks | Grip strength was measured with Jamar Dynamometer |
| change of Pinch strength | Baseline, 6, 12, 24 weeks | Pinch strength was measured with Jamar pinch gauge |
| change of Dexterity | Baseline, 6, 12, 24 weeks | Dexterity was measured with Purdue Pegboard test |
| change of Quality of Life | Baseline, 6, 12, 24 weeks | Quality of Life was measured with LupusQoL Questionnaire |
Countries
Greece
Outcome results
None listed