Mass Continous Suture With PDS Versus Interrupted Suture With Thread on Major Abdominal Incision

Mass Continuous Suture With PDS Versus Interrupted Suture With Thread on Major Abdominal Incision: A Randomized Controlled Trial

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT03801421

Enrollment

2000

Registered

2019-01-11

Start date

2019-02-01

Completion date

2021-03-16

Last updated

2021-05-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Surgical Wound, Suture, Complication

Keywords

Surgical Wound, Suture, Complication

Brief summary

A better suture technology will reduce postoperative incision complications. This study is designed to compare mass continous suture with PDS and interrupted suture with thread on major abdominal incision.

Detailed description

A better suture technology will reduce postoperative incision complications. The previous retrospective cohort study from the investigator has demonstrated that continuous mass suture with PDS led to shorter incision closure time, early wound healing and comparable incisional complications versus interrupted thread suture. As such, the current RCT study will include 100 subjects with major abdominal incision. They will be divided into two groups randomly: Mass suture gorup, mass continuous suture with PDS, Control group, interrupted suture with thread. The wound healing time, stitches removal time and incidence of incision complications will be compared between the two groups.

Interventions

PROCEDUREMass continous suture with PDS

The surgical incision will be treated by mass continous suture with PDS.

PROCEDUREInterrupted suture with thread

The surgical incision will be treated by interrupted suture with thread.

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to 65 Years

Healthy volunteers

Inclusion criteria

* the patient with major abdominal incision. * the incision is longer than 10 cm * aged between 18 to 65 years old

Exclusion criteria

* Pregnant woman * Patient with diabetes * Patient with a history of cardiovascular disease, including coronary heart disease and stroke. * Severe lung diseases such as COPD and asthma * Patients undergoing emergent or infectious surgery * Patients with surgical site infection * No autonomy, inability or unwillingness to participate in follow-up

Design outcomes

Primary

Measure	Time frame	Description
healing time, d (day)	Up to 1 month after surgery	Time duration between the date of surgery to the date of stitches off

Secondary

Measure	Time frame	Description
incidence of incision complications	Up to 1 month after surgery	The incision complications include infection, dehiscence, fat liquefaction, and so on.

Countries

China

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026