Walled Off Pancreatic Necrosis (WON)
Conditions
Brief summary
This is a retrospective chart review study examining 1) demographic data such as age, sex, etiology of pancreatitis 2) clinical data including radiological characteristics of walled off pancreatic necrosis, walled off necrosis related admissions and readmission following endoscopic drainage, surgical or percutaneous procedures performed for the management of walled off pancreatic necrosis, and clinical outcomes following treatment of WON (including hospital readmissions, WON resolution, procedure complications, WON related death) 3) endoscopy data including indication for initial endoscopic drainage and subsequent endoscopic procedures performed for management of walled off necrosis (including additional EGD's, endoscopic drainage procedures, and/or necrosectomy)
Interventions
PROCEDUREendoscopic drainage of walled off pancreatic necrosis
transmural drainage and mechanical debridement of solid debris (necrosectomy)
Sponsors
University of Oklahoma Medical Center
Northwestern University Chicago Illinois
St. Luke's Hospital, Kansas City, Missouri
Washington University School of Medicine
Study design
Observational model
CASE_CONTROL
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
19 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Patients over 18 years of age who underwent endoscopic drainage of walled off pancreatic necrosis * Patients who did not require further intervention (either surgical, percutaneous, or endoscopic) following endoscopic drainage * Patients who required further intervention for walled off pancreatic necrosis (either surgical, percutaneous, or endoscopic) following endoscopic drainage. * Patients who underwent percutaneous or surgical interventions prior to endoscopic drainage
Exclusion criteria
* Pancreatic pseudocysts without any solid debris * Under 18 years of age at the time of endoscopic drainage
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Identify WON imaging characteristics on cat-scan | through study completion, an average of 260 days | Characteristics on cat-scan that are predictive of requiring multiple endoscopic procedures, percutaneous drainage, and/or surgical intervention for management of walled off pancreatic necrosis |
| Endoscopic course (total number and type of endoscopic treatments required for resolution of walled off necrosis, occurrence of treatment related complications) | through study completion, an average of 260 days | Imaging classification method to efficiently report these imaging characteristics |
| Clinical course (number of hospital readmissions during treatment, rates of walled off necrosis resolution, rates of walled off necrosis related death) | through study completion, an average of 260 days | Characteristics to develop a predictive model that will help to identify patients at high risk for requiring multiple endoscopic procedures, percutaneous drainage, and/or surgical intervention for management of walled off pancreatic necrosis. |
Countries
United States
Outcome results
None listed