Metabolic Surgery
Conditions
Keywords
metabolic surgery, metabolic disease, multicenter
Brief summary
Metabolic surgery, as a recognition treatment option for patients with clinical morbid obesity, is gaining increasing appreciation. In addition to substantial weight loss, emerging studies have highlighted that metabolic surgery can substantially ameliorate obesity-related metabolic diseases, including but not limited to type 2 diabetes mellitus (T2DM), hypertension, dyslipidemia, obstructive sleep apnea-hypopnea syndrome (OSAHS) and polycystic ovary syndrome (PCOS)in severely obese patients. However, further investigations with larger sample size and longer observation time still needed to clarity the efficacy and safety of metabolic surgery in Chinese patients with obesity and encouraging future research in this field.
Interventions
None listed
Sponsors
Beijing Tiantan Hospital
Beijing Shijitan Hospital, Capital Medical University
Beijing Hospital
Peking Union Medical College Hospital
Shanxi Dayi Hospital
The Second Hospital of Hebei Medical University
Tianjin Medical University General Hospital
Inner Mongolia People's Hospital
Henan Provincial People's Hospital
Qilu Hospital of Shandong University
The First Hospital of Hebei Medical University
The Second People's Hospital of Xinxiang Henan
Tangshan Gongren Hospital
Tianjin Nankai Hospital
Tianjin First Central Hospital
Beijing Friendship Hospital
Study design
Observational model
CASE_ONLY
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Healthy volunteers
No
Inclusion criteria
* be able to receive metabolic surgery, including but not limit to LSG and LRYGB
Exclusion criteria
* can not be able to understand and willing to participate in this registry with signature
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| the excess weight loss effect of different metabolic surgeries after 1year | 1 year after surgery | Percent excess weight loss (%EWL), %EWL=\[(initial weight)-(post-op weight)\]/\[(initial weight)-(ideal weight)\] (in which ideal weight is defined by the weight corresponding to a BMI of 25 kg/m2) |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| the adverse events rate of different metabolic surgeries | 30 days after surgery | show the surgical safety by 30 days follow-up according to guideline（such as: bleeding, leak, obstruction, re-operation for complication） |
| the excess weight loss effect of metabolic surgery with long-time follow-ups | 3 years | Percent excess weight loss (%EWL), %EWL=\[(initial weight)-(post-op weight)\]/\[(initial weight)-(ideal weight)\] (in which ideal weight is defined by the weight corresponding to a BMI of 25 kg/m2) |
| the glycemic control level of metabolic surgery with long-time follow-ups | 1 year after surgery | the change of HbA1c, glucose level, C-peptide and insulin levels |
Countries
China
Outcome results
None listed