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Early Debridement Within 24 Hours After Surgery for Wound Healing of Abdominal Incision

Early Debridement Within 24 Hours After Surgery Compared Routine Debridement (24 Hours Later) for Wound Healing of Abdominal Incision

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT03798041
Enrollment
480
Registered
2019-01-09
Start date
2019-02-01
Completion date
2021-03-16
Last updated
2021-12-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Surgical Wound

Keywords

Surgical Wound, Suture, Complication

Brief summary

Wound healing after surgery is a complex procedure. Liquefaction of the fat and necrosis of inactivated tissue, as well as blood clots are always accumulated mostly within 24 hours after surgery. As such, early debridement within 24 hours after surgery might improve the healing of the wounds. This study is designed to compare the impact of early debridement of the wound versus regular dressing (24 hours later) on the wound healing. 100 patients will be included in this study, and divided into 2 groups randomly. Then, the healing of the wound, stitch removal time, incidence of incision complications will be compared between the two groups.

Interventions

BEHAVIORALDebridement Within 24 Hours After Surgery

Debrided within 24 hours after surgery

Sponsors

First Affiliated Hospital Xi'an Jiaotong University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
No

Inclusion criteria

* the patient with major abdominal incision.

Exclusion criteria

* Pregnant woman * Patient with diabetes * Patient with a history of cardiovascular disease, including coronary heart disease and stroke. * Severe lung diseases such as COPD and asthma * Patients undergoing emergent surgery or infectious surgery * Patients with surgical site infection or abdominal abscess * No autonomy, inability or unwillingness to participate in follow-up

Design outcomes

Primary

MeasureTime frameDescription
healing time, d (day)From date of surgery to the date of stitches off (up to 1 month)since the ending of surgery to stitches off.

Secondary

MeasureTime frameDescription
incidence of incision complicationsFrom the date of surgery to stitches off (up to 1 month)The incision complications include infection, dehiscence, fat liquefaction, etc.

Countries

China

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026