Muscle Weakness, Parkinson Disease, Respiration; Decreased, Surgery
Conditions
Brief summary
Parkinson's disease is a progressive chronic neurodegenerative disease. In cases where drug treatment is insufficient and drug use is not possible due to drug side effects, highly effective and low-risk surgical treatment options could be used. In Parkinson's Disease; findings such as chest wall rigidity and weakness of the respiratory muscle strength occur. The aim of this study was to determine the effect of preop and postop DBS surgery on respiratory muscle strength, respiratory function and physical performance in patients with Parkinson's disease.
Detailed description
In the study, at least 10 patients with Parkinson's disease who had DBS surgery in Mustafa Kemal University Research and Practice Hospital, Department of Brain and Nerve Surgery will be evaluated. Demographic-physical features, pulmonary functions, respiratory muscle strength, exercise capacity, functionality, and muscle strength will be evaluated
Interventions
DEVICEMIP and MEP
Pre-op, Post-op of, 1 month after surgery, 3 months after surgery
Sponsors
Mustafa Kemal University
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
SUPPORTIVE_CARE
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
40 Years to 70 Years
Healthy volunteers
No
Inclusion criteria
* Lack of any neurological disease other than Parkinson's * DBS surgery to be performed in the STN region
Exclusion criteria
* Patients with advanced cognitive impairment * Patients with pulmonary, neurological and orthopedic diseases affecting functionalities * Pregnancy * Patients in whom the stimulation was canceled due to infection after surgery.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Functional exercise capacity | Change from Baseline Functional exercise capacity at 3 months(Pre-op,Post-op Off, Post-op 1. month, Post-op 3. Month), an average of 3 months | 6 minute walking test |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Pulmonary functions | Change from Pulmonary functions at 3 months(Pre-op,Post-op Off, Post-op 1. month, Post-op 3. Month), an average of 3 months | Spirometry |
| Inspiratory and expiratory muscle strength (MIP, MEP) | Change from Inspiratory and expiratory muscle strength (MIP, MEP) at 3 months(Pre-op,Post-op Off, Post-op 1. month, Post-op 3. Month), an average of 3 months | Mouth pressure device |
| Muscle strength | Change from Peripheral muscle strength at 3 months(Pre-op,Post-op Off, Post-op 1. month, Post-op 3. Month), an average of 3 months | Muscle Testing Device (N) |
| Grip Test (Peripheral muscle strength) | Change from Peripheral muscle strength at 3 months(Pre-op,Post-op Off, Post-op 1. month, Post-op 3. Month), an average of 3 months | Hand Held Dynamometer (kgf) |
Countries
Turkey (Türkiye)
Contacts
Primary ContactDeran Oskay, PhD
Backup ContactBircan Yucekaya, MSc
Outcome results
None listed