Protein Ingestion and Skeletal Muscle Atrophy

Understanding the Role of Protein Ingestion on Skeletal Muscle Atrophy During an Acute Period of Disuse

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT03797781

Enrollment

Registered

2019-01-09

Start date

2017-10-31

Completion date

2019-12-31

Last updated

2020-09-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Muscle Atrophy

Brief summary

The effect of different protein intakes on skeletal muscle atrophy during short term unilateral leg immobilisation.

Interventions

OTHERLower limb immobilisation (leg brace) with varying levels of protein intake

Single leg immobilisation via leg brace and crutches, the groups have different amounts of protein intake

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

BASIC_SCIENCE

Masking

SINGLE (Subject)

Eligibility

Sex/Gender

MALE

Age

18 Years to 35 Years

Healthy volunteers

Yes

Inclusion criteria

* BMI \>18 and \<28 no prescription medications or current illness.

Exclusion criteria

* BMI \<18 and \>28 current prescription medication no history of leg injury. * Smoker * Medical conditions including (cardiovascular disease ((e.g. hypertension)), metabolic disease ((e.g. type 2 diabetes)), any personal or family history of deep vein thrombosis.

Design outcomes

Primary

Measure	Time frame
Muscle size	3 days

Secondary

Measure	Time frame
Muscle strength	3 days

Countries

United Kingdom

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 18, 2026