Cancer, Radiotherapy
Conditions
Keywords
survival, cancer, palliative, radiotherapy, prognosis
Brief summary
Many patients with incurable cancer will receive palliative oncological treatment before their death, and radiotherapy (RT) is an important element of this. The aim of palliative RT is to alleviate symptoms and improve quality of life. An accurate and practical survival prediction model for metastatic cancer patient receiving palliative RT can assist the decision making (ranging from best supportive treatment alone for expected short survival, to dose escalation for potential better disease control). The available survival prediction models (such Survival Prediction Score using Number of Risk Factors by Chow et al and TEACHH model) have been developed in the Western world. We therefore perform a prospective observational study 1) to assess the overall survival of patients evaluated for palliative RT at a tertiary hospital in Hong Kong, and 2) to validate the prognostic score systems in our population.
Interventions
RADIATIONpalliative radiotherapy
Radiotherapy for palliating symptoms in stage IV cancer patients
Sponsors
Tuen Mun Hospital
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* All adult patients with stage IV cancer who are referred for palliative RT in Tuen Mun Hospital, including both inpatients and outpatients.
Exclusion criteria
* Patients who have received palliative RT before (i.e. not the first course palliative RT), have non-metastatic disease, are misclassified as palliative patients.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Overall Survival | 1 year | Overall Survival in the studied population |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Overall Survival in Each Indication of Palliative Radiotherapy | 3, 6, 9, 12 months | Indications of Palliative Radiotherapy: The indication will be as follow: spinal cord compression brain metastases tumor bleeding tumoral mass Cancer pain Superior Vena Cava Syndrome/ Airway compression |
| Overall Survival by Survival Prediction Model (NRF) | 3, 6, 9, 12 months | Overall Survival by Survival Prediction Score using Number of Risk Factors (NRF) |
| Overall Survival by Survival Prediction Model (TEACHH) | 3, 6, 9, 12 months | Overall Survival by Survival Prediction Score using TEACHH Model |
Countries
Hong Kong
Contacts
Primary ContactShing Fung Lee, MBBS (HK), FRCR (UK)
Outcome results
None listed