Does Myomectomy for Intramural Fibroid Improve ART Outcome?

Does Myomectomy for Intramural Fibroid Improve ART Outcome? A Randomized Controlled Trial

Status

UNKNOWN

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT03796130

Acronym

MIFART

Enrollment

Registered

2019-01-08

Start date

2019-12-01

Completion date

2021-04-30

Last updated

2019-12-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Fibroid Uterus

Brief summary

Intamural fibroids (myoma) do exist in some infertile women undergoing IVF treatment. There is controversy whether myomectomy before IVF treatment could improve IVF outcome. This trial will examine whether myomectomy in those patients could improve the results.

Detailed description

This study will include women who have intramural myoma ranging from 3-5 cm The participants will be randomly allocated into two groups. In group (1): myomectomy will be performed before ART In group (2):women will have their trial of ART without myomectomy In group A, ART will be performed 3 months after myomectomy if the uterine cavity is not opened and 6 months after myomectomy upon inadvertent opening of the uterine cavity during surgery

Interventions

PROCEDUREMyomectomy

This study will include women who have intramural myomas ranging from 3-5 cm The participants will be randomly allocated into two groups. In group (1): myomectomy will be performed before ART In group (2):women will have their trial of ART without myomectomy In group A, ART will be performed 3 months after myomectomy if the uterine cavity is not opened and 6 months after myomectomy upon inadvertent opening of the uterine cavity during surgery

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

SINGLE (Outcomes Assessor)

Eligibility

Sex/Gender

FEMALE

Age

18 Years to 35 Years

Healthy volunteers

Inclusion criteria

* Inclusion criteria: * Women with intramural fibroid without any cavity involvement * Age ˂ 35 years * I onCSI or IVF cycles * normal uterine cavity

Exclusion criteria

Design outcomes

Primary

Measure	Time frame	Description
The primary outcome will be ongoing pregnancy rate	3 months after embryo transfer	Pregnancy continued after 12 week gestation per randomised women

Secondary

Measure	Time frame
-Implantation rate	15 days after embryo transfer
-clinical pregnancy rate	5 weeks after embryo transfer

Countries

Egypt

Contacts

Primary ContactEman ElGindy, MD, PhD

eman_elgindy2013@hotmail.com01227491143

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026