After Surgery Acute Renal Failure Incidence in Total Knee Arthroplasty With and Without Tourniquet

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT03795805

Enrollment

100

Registered

2019-01-08

Start date

2018-03-15

Completion date

2018-12-20

Last updated

2019-01-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute Kidney Injury, Arthroplasty, Replacement, Knee, Knee Osteoarthritis, Tourniquets

Brief summary

This study analize the incidence of acute renal failure after performing total knee arthroplasty with or without use of tourniquet limb cuff (half of patients for each group) in a randomized clinical trial

Detailed description

This study analize the incidence of acute renal failure after performing total knee arthroplasty with or without (using local intraarticular anesthesia) use of tourniquet limb cuff (half of patients for each group) in a randomized clinical trial

Interventions

PROCEDUREtotal knee arthroplasty

Total knee arhroplasty

PROCEDURETourniquet limb cuff

Tourniquet limb cuff and regular anesthesia

DRUGIntaarticular lidocain

20 ml of 2% lidocain application intraarticular before surgery (intraarticular lidocain)

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

PREVENTION

Masking

DOUBLE (Subject, Outcomes Assessor)

Intervention model description

Randomized Clinical Trial

Eligibility

Sex/Gender

ALL

Age

18 Years to 99 Years

Healthy volunteers

Yes

Inclusion criteria

* Patients knee arthrosis * Required a surgical treatment with Total Knee Arthroplasty

Exclusion criteria

* Not accept to be in the study * Not signed consent form * Not having blood sample for creatinin meassure

Design outcomes

Primary

Measure	Time frame	Description
Creatinin before surgery	Creatinin before surgery	Blood Creatinin meassure in mg/dl before surgery
Creatinin after surgery 1	Creatinin after surgery 1 at 24 hours	Blood Creatinin meassure in mg/dl at 24 hours
Creatinin after surgery 2	Creatinin after surgery 2 at 48 hours	Blood Creatinin meassure in mg/dl at 48 hours

Countries

Mexico

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026