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Validation of a Record-based Frailty Assessment According to the Multidimensional Prognostic Index

Validation of a Record-based Frailty Assessment According to the Multidimensional Prognostic Index

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT03794674
Enrollment
92
Registered
2019-01-07
Start date
2018-12-04
Completion date
2019-02-22
Last updated
2019-10-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Frail Elderly Syndrome

Keywords

Multidimensional Prognostic Index, Frailty, Geriatric, Elderly, Aged, +75, Comprehensive Geriatric Assessment

Brief summary

Background Various phenotype and cumulative frailty assessment tools have been developed and compared in research. For use in an in-hospital setting, a cumulative and graded frailty assessment method is preferred in order to identify subgroups of patients at risk of adverse events during discharge and transition to primary care. Comprehensive Geriatric Assessment (CGA) is the gold standard to assess frailty. Most medical wards have limited access to specialized geriatric team support capable of performing CGA. Thus in these wards there is a need for a CGA based instrument to identify the frail patients and to quantify the level of frailty. The Multidimensional Prognostic Index (MPI) is based on CGA and is a comprehensive cumulative deficit frailty assessment tool validated in a Danish geriatric department. MPI is fully applicable in the everyday clinical work and supplies useful information to clinicians. It can predict readmission and death, and it is well-suited to assess the degree of frailty. Enabling identification of patients at risk of adverse events facilitates targeting of the interventions in order to improve patient outcomes. The MPI is a bedside assessment. However, in observational record-based research the patient is not accessible for the researcher. To assess and identify hospitalized frail patients retrospectively for clinical research, a valid record-based frailty assessment method is needed. The aim of this study is to compare the accuracy of a record-based MPI assessment with a bedside performed MPI assessment in order to use the record-based MPI when access to bedside MPI is impossible.

Interventions

OTHERNo intervention.

No intervention, since this is a validation study

Sponsors

University of Aarhus
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
OTHER

Eligibility

Sex/Gender
ALL
Age
75 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Acutely admitted to one of the two medical departments listed below * Aged 75 years or older * Living within the municipality of Aarhus

Exclusion criteria

* Included in any other kind of follow-up schemes * Already included in this study * Declared terminally ill or undergoing palliative care at admission * Admitted from one specific temporary nursing home with geriatric medical assistance (Vikærgården) * Discharge or transfer to another department, including hospice * The patient does not want to participate in the MPI-screening process

Design outcomes

Primary

MeasureTime frameDescription
Sumscore1 dayThe relative difference between the two measurements' sumscores calculated as an Intraclass Correlation Coefficient (ICC)

Countries

Denmark

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026