Attempted Suicide
Conditions
Keywords
Suicide, Suicidal ideation, Sleep disorder
Brief summary
Several studies have demonstrated an association between sleep disorders such as insomnia and nightmares to suicidal ideations and behaviors. Nevertheless, some of these studies are methodologically questionable especially in the exploration of sleep disorders. Furthermore, confounding factors such as depressive symptomatology are not controlled and the measurement of suicidal behavior has often been taken into account as a historical measure, not as a current event, which introduces uncertainties and a lack of precision regarding the temporality of the phenomena. Today, while the links between sleep disorders and suicidal risk are well known, we have a lack of information on the importance and the role of sleep disorders as a precipitating factor. Indeed, few studies have evaluated the temporal link between sleep disorders and suicidal acts. The objective of this study is to evaluate the links between acute and chronic sleep disorders and the risk of suicide attempt
Detailed description
Pilot, prospective, monocentric case-control study. There are 2 groups of subjects : * group of patients who have made a suicide attempt * control group with only suicidal ideas First visit V1 is performed within the first 72 hours of hospitalization. A re-assessment is scheduled 1 month after (V2). At V1, collected parameters are : chronic sleep disorders, chronotype, specific sleep disorders in posttraumatic stress disorder, nightmares and the distress associated, childhood trauma, cognitive dysfunction, suicidal ideation and psychopathologic assessment. At V2, we assess evolution of sleep disturbances and suicidal ideation.
Interventions
None listed
Sponsors
University Hospital, Lille
Study design
Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
Criterion specific to the studying group : \- Subjects hospitalized and whose indication of hospitalization is a suicide attempt by voluntary drug intoxication or phlebotomy during the last 72 hours, without any history of attempted suicide Criterion specific to the control group: \- Subjects hospitalized since less than 72 hours, and whose indication of hospitalization is the presence of suicidal ideas, without any history of attempted suicide
Exclusion criteria
* Pregnant of lactating women * Diagnosed dementia pathology * Proven intellectual disability * Patient whose physical or mental state does not allow the passing of the tests of the study * Under protective measures (guardianship/supervision) * Refusal to participate in the study * Diagnosed with chronic or severe psychiatric illness (psychotic disorder, bipolarity)
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Sleep disorders intensity by the Insomnia Severity Index (ISI) | at the 48 hours after the hospitalization; at the maximum within 72 hours. | ISI score in the last 2 weeks between a group of suicide attempts and a group with suicidal thoughts suicidal The Insomnia Severity Index has seven questions. The seven answers are added up to get a total score. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Correlation between Beck Suicide Intent Scale (BSIS) score and ISI score | Baseline (visit inclusion) and at one month ago | Correlation between Beck Suicide Intent Scale (BSIS) score and ISI score The Suicide Intent Scale (SIS) wconsists of 15 questions which are scaled from 0-2, which take into account both the logistics of the suicide attempt as well as the intent. The scale has high reliability and validity. Completed suicides ranked higher in the severity of the logistics than attempted suicides (it was impossible to measure intent for the completed suicides), and those with multiple attempts had higher scores than those who only attempted suicide once |
| Evolution of ISI score | At one month +/- 15 days ant at 3 months +/-3 weeks | Assess the evolution of sleep disturbances for each group by ISI Score |
| Chronotype classification by MCTQ | at the 48 hours after the hospitalization; at the maximum within 72 hours;at 3 months +/-3 weeks | Exploratory descriptive measures in the 2 groups |
| Pittsburg Sleep Quality Index (PSQI) score | at the 48 hours after the hospitalization; at the maximum within 72 hours,at 3 months +/-3 weeks | PSQI score between the groups PSQI is a self-report questionnaire that assesses sleep quality over a 1-month time interval. The measure consists of 19 individual items, creating 7 components that produce one global score, and takes 5-10 minutes to complete. |
| Childhood Trauma Questionnaire (CTQ) score | at the 48 hours after the hospitalization; at the maximum within 72 hours. | CTQ score between the groups The Childhood Trauma Questionnaire was developed as a screening tool for histories of abut and neglect. The self-report includes a 28-item test that measures 5 types of maltreatment - emotional, physical, and sexual abuse, and emotional and physical neglect. |
| Montréal Cognitive Assessment (MocA) | at the 48 hours after the hospitalization; at the maximum within 72 hours. | cognitive assessment by Moca test |
Countries
France
Contacts
PRINCIPAL_INVESTIGATORVincent JARDON, MD
University Hospital, Lille
Outcome results
None listed